• Articles

    Current Concepts in Concussion: Initial Evaluation and Management

    Keith A. Scorza, Wesley Cole

    Concussion results from trauma to the head; it affects individuals physically, cognitively, and emotionally/behaviorally and is a major health concern. Headache is the most common symptom. Spine and serious brain injuries should be ruled out before diagnosis. Symptom...

    Abnormal Uterine Bleeding in Premenopausal Women

    Noah Wouk, Margaret Helton

    Abnormal uterine bleeding is a common symptom in reproductive-aged women. The acronym PALM-COEIN facilitates the classification of bleeding, with PALM referring to structural etiologies (polyp, adenomyosis, leiomyoma, malignancy and hyperplasia), and COEIN referring to...

    Febrile Seizures: Risks, Evaluation, and Prognosis

    Dustin K. Smith, Kerry P. Sadler, Molly Benedum

    A febrile seizure is a seizure occurring in a child six months to five years of age that is accompanied by a fever (100.4°F [38°C] or greater) without central nervous system infection. It can be simple or complex. Children who have a simple febrile seizure and are well...


    Understanding the High Cost of Insulin: What Family Physicians Can Do to Help Our Patients with Type 2 Diabetes Mellitus

    Randi Sokol

    Through clinical and system-level interventions, family physicians can push back against the high cost of insulin and help patients with type 2 diabetes afford these essential medications.


    Will a Feeding Tube Help? Deciding for a Father at the End of Life

    Leah B. Rosenberg

    Making caring, difficult choices on behalf of loved ones at the end of life.

    Cochrane for Clinicians

    Pulse Oximetry Screening for Critical Congenital Heart Defects in Newborns

    Tyler Barreto

    Pulse oximetry is an accurate screening test for critical congenital heart defects in newborns. Pulse oximetry is simple to use, widely available, and has moderate sensitivity (76.3%) and good specificity (99.9%). However, the prevalence of critical congenital heart defects...

    Direct Oral Anticoagulants vs. Warfarin to Prevent Stroke and Embolic Events in Patients with Atrial Fibrillation and CKD

    John W. Lax, Racheal Wood, Christopher E. Jonas

    Direct oral anticoagulants are as likely as warfarin to prevent all strokes and systemic embolic events in patients with atrial fibrillation and CKD stage 3. They do not increase the risk of major bleeding events. The evidence remains insufficient to make recommendations for...

    AFP Clinical Answers

    Testicular Cancer, Onset of Labor, Respiratory Tract Infection, Thyroid Cancer, Running Injuries

    How should testicular cancer be diagnosed? | Does the time between contractions help predict when a pregnant woman at term should present for labor evaluation? | Are broad-spectrum antibiotics the preferred treatment in children with acute respiratory tract infections? |...

    Photo Quiz

    Subcutaneous Nodules on the Chest, with Cough and Weight Loss

    Darrell R. Over, J. Brett McCutcheon

    A 60-year-old smoker presented with cough and hemoptysis. She had also developed several subcutaneous masses on her chest wall and left and right abdominal wall over the past several months.

    FPIN's Help Desk Answers

    Maternal Pertussis Vaccination During Pregnancy

    John B. Waits, Lacy Smith, Daniel J. Hurst

    Women should receive the Tdap vaccine during pregnancy regardless of previous immunization history. Infants whose mothers received prenatal immunization had 50% fewer cases of pertussis compared with those whose mothers received postpartum immunization.

    Curbside Consultation

    Palliative Care in Advanced Dementia

    Scott Endsley, Rachel Main

    What is the best way for family physicians to determine prognosis and applicability of palliative care for patients with dementia?


    Guideline, with No Evidence, Suggests Annual Screening for Urinary Incontinence in Women

    Allen F. Shaughnessy

    The goal of screening is to identify a disorder before it becomes symptomatic if early treatment has the potential for greater benefit than waiting until symptoms are reported. Despite the failure to meet this definition, this guideline suggests annual screening of women for...

    Aspirin's Benefits and Harms Are Less Clear for Primary Prevention in Moderate-Risk Patients

    Henry C. Barry

    No Reduction in Delirium with the Use of Haloperidol or Ziprasidone in Critically Ill Patients

    Nita Shrikant Kulkarni

    For patients with acute respiratory failure or shock who develop delirium in the intensive care unit (ICU), the use of haloperidol or ziprasidone (Geodon) does not reduce the duration of delirium. This trial was powered to detect at least a two-day difference in the duration...

    Statins Ineffective for Primary Prevention of Cardiovascular Disease in Patients 75 Years or Older Without Diabetes Mellitus

    Allen F. Shaughnessy

    In this retrospective study, statin treatment in patients 75 years or older without preexisting CVD did not change the likelihood of developing CVD or reduce any-cause mortality. However, patients 75 to 84 years of age with diabetes mellitus benefitted from treatment. These...

    Practice Guidelines

    Mild TBI in Children: Guidance from the CDC for Diagnosis and Treatment

    Lisa Croke

    Mild traumatic brain injury in children is a major problem in the United States. Based on a systematic literature review, the Centers for Disease Control and Prevention (CDC) released recommendations specific to children with Glasgow Coma Scale scores of 13 to 15.

    Medicine by the Numbers

    HPV Vaccine for Prevention of High-Grade Precancerous Cervical Lesions

    Anthony Garzone, Matthew Schorr, Tyler Rogers

    Data suggest the benefits of HPV vaccination for reducing precancerous lesions outweigh the potential harms. Find out more.

    Letters to the Editor

    Alternate Nasal Packing Technique for Patients Experiencing Epistaxis


    All editors in a position to control content for this activity, AFP journal, are required to disclose any relevant financial relationships. View disclosures.

    Tag Legend


    CME Continuing Medical Education Credit
    POC Point-of-Care Resource
    FREE Free Access
    Alg Algorithm
    DDx Differential Diagnosis
    PtEd Patient Education