December 1, 2020

Seasonal affective disorder is a variant of major depressive disorder or bipolar disorder. It is characterized by depressive symptoms that occur at a specific time of year, typically fall or winter, with full remission at other times of year. Possible risk factors include…

The annual installment of this series summarizes the top POEMs (patient-oriented evidence that matters) of 2019 that are consistent with the Choosing Wisely campaign. These POEMs were highly rated by physician members of the Canadian Medical Association for their clinical…

Parkinson disease is a progressive neurodegenerative disorder with significant morbidity and mortality. The diagnosis of Parkinson disease is clinical, and key disease features are bradykinesia, rigidity, and tremor. Parkinson disease progression is variable, and clinical signs…

Primary care plays a large role in the management of acute pain; therefore, the American College of Physicians and the American Academy of Family Physicians developed a clinical practice guideline for the nonpharmacologic and pharmacologic management of acute pain from non–low…

Key clinical questions and their evidence-based answers directly from the journal’s content, written by and for family physicians.

In patients without diabetes mellitus who have chronic kidney disease, is a low-protein diet effective at preventing progression to end-stage renal disease or the need for dialysis?

Compared with placebo, beta-blocker use in patients with acute MI reduces short-term (less than three months) risk of MI and long-term (more than three months) risk of cardiovascular mortality and all-cause mortality.

In this well-conducted systematic review, FOBT, although useful in screening for colorectal cancer, is not highly accurate in evaluating patients with clinical indications.

A label of penicillin allergy clears the shelves of many effective treatments for various infections. A simple rule outlined in the synopsis effectively identifies (without allergy testing) low-risk penicillin allergies in patients with a history of a penicillin allergy event.

Bleeding decreased over time for most women after the insertion of a levonorgestrel-releasing intrauterine system.

Some treatments can improve cognition on research scales, but daily function will not be affected in a noticeable way. Managing behavioral or psychological issues with medication is not supported by current evidence

A 51-year-old patient presented with several years of diffuse shoulder pain and abnormal imaging findings.

The American Academy of Family Physicians and the American College of Physicians have published guidelines based on a systematic review and network meta-analysis of 207 studies involving 32,959 patients that evaluated treatments for acute musculoskeletal pain other than low…

The mainstay of treatment for uncomplicated diverticulitis has been antibiotic therapy with bowel rest. However, recent studies have questioned the role of antibiotics.

Children treated for cancer do not retain full immunity from previous vaccinations; therefore, it is likely beneficial for children who survive cancer to be revaccinated six to 12 months after immunosuppressive therapy.

Reply: Karl T. Clebak