Genito-pelvic pain/penetration disorder is a relatively new term encompassing both dyspareunia (recurrent pain with intercourse) and vaginismus (involuntary contraction of the pelvic floor with attempted penetration). Symptoms are often multifactorial. Thus, a detailed history and sensitive patient-centered examination are essential to identify and treat the underlying cause(s). Additional laboratory or imaging studies are not routinely indicated but may be helpful to rule out infectious etiologies or evaluate pelvic organ pathology in cases of deep dyspareunia. Treatment may include patient education about the condition, avoidance or modifications of irritants or triggers, use of vaginal lubricants and moisturizers, hormone therapy, pelvic floor physical therapy, and psychosocial interventions as indicated. Vulvodynia is a separate but related condition and is a diagnosis of exclusion. It is defined as vulvar pain for at least 3 months without another clearly identifiable cause. High-quality studies on the treatment of vulvodynia are limited. However, pelvic floor physical therapy and psychosocial interventions such as cognitive behavior therapy have the most consistent evidence of benefit.
Case 1. TL is a 54-year-old patient with diabetes that is well-controlled with metformin. She presents for a routine physical and cervical cancer screening. When asked about sexual health, she initially laughs and describes it as “nonexistent.” Asked for clarification, TL says she has not had vaginal sex for more than a year because it is too painful. She has tried several over-the-counter products to relieve pain and vulvar itching and burning without improvement. She says she has difficulty discussing this with you or her partner, but it causes significant personal and relationship distress.
Dyspareunia
BACKGROUND
Dyspareunia (recurrent pain before, during, or after intercourse) and vaginismus (involuntary contraction of the pelvic floor muscles with attempted vaginal penetration) are common conditions that can cause significant distress and diminished quality of life. Genito-pelvic pain/penetration disorder is a relatively new term encompassing both dyspareunia and vaginismus that recognizes the overlap in symptoms and etiologies between the two (Table 1).1
Table 1 DSM-5 Criteria for Genito-Pelvic Pain/Penetration Disorder
| A. Persistent or recurrent difficulties with one (or more) of the following: |
| 1. Vaginal penetration during intercourse. |
| 2. Marked vulvovaginal or pelvic pain during vaginal intercourse or penetration attempts. |
| 3. Marked fear or anxiety about vulvovaginal or pelvic pain in anticipation of, during, or as a result of vaginal penetration. |
| 4. Marked tensing or tightening of the pelvic floor muscles during attempted vaginal penetration. |
| B. The symptoms in Criterion A have persisted for a minimum duration of approximately 6 months. |
| C. The symptoms in Criterion A cause clinically significant distress in the individual. |
| D. The sexual dysfunction is not better explained by a nonsexual mental disorder or as a consequence of severe relationship distress (eg, partner violence) or other significant stressors and is not attributable to the effects of a substance/medication or other medical condition. |
| Specify whether: |
| Lifelong: The difficulty has been present since the individual became sexually active. |
| Acquired: The difficulty began after a period of relatively normal sexual function. |
| Specify current severity: |
| Mild: Evidence of mild distress over the symptoms in Criterion A. |
| Moderate: Evidence of moderate distress over the symptoms in Criterion A. |
| Severe: Evidence of severe or extreme distress over the symptoms in Criterion A. |
DSM-5 = Diagnostic and Statistical Manual of Mental Disorders, 5th ed.
Reprinted with permission from Diagnostic and Statistical Manual of Mental Disorders. 5th ed. American Psychiatric Association; 2013:437.
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