• Articles

    Peripheral Nerve Entrapment and Injury in the Upper Extremity

    Sabrina Silver, Christopher C. Ledford, Kendall J. Vogel, James J. Arnold

    Peripheral nerves in the upper extremities are at risk of injury and entrapment because of their superficial nature and length. Injury can result from trauma, anatomic abnormalities, systemic disease, and entrapment. Most peripheral nerve injuries seen by family physicians...

    Difficult-to-Treat and Severe Asthma: Management Strategies

    Krishnan Narasimhan

    In difficult-to-treat asthma, the disease is uncontrolled despite adherence to inhaled corticosteroid therapy in combination with a second controller, an oral corticosteroid is needed to achieve control, or it is uncontrolled despite oral corticosteroid therapy. Severe asthma...

    Initiating Hormonal Contraception

    Ruth Lesnewski

    Most patients can safely begin using hormonal contraception at any point during their menstrual cycle. A flexible, patient-centered approach to initiating contraception promotes health and enhances patients' reproductive autonomy. A recent Papanicolaou test is not necessary...


    Enhancing Diabetes Self-Management Education and Support in Clinical Practice

    Beulette Y. Hooks

    Health systems and family physicians should mobilize to ensure that all people with type 2 diabetes have access to diabetes self-management education and support, including nutritional, physical, and emotional support.

    AFP Clinical Answers

    Antidepressants for Older People, Point-of-Care Ultrasonography, BRCA Testing, Probiotics

    What are the adverse events of antidepressants in adults 65 years and older with major depressive disorder? | What urgent medical conditions can be diagnosed by point-of-care ultrasonography? | Which women are recommended for breast cancer susceptibility 1 and 2 (<i>BRCA 1/2<...

    Cochrane for Clinicians

    Alcoholics Anonymous and Other 12-Step Facilitation Programs for Alcohol Use Disorder

    Elizabeth Salisbury-Afshar, Glenn Kauppila

    Manualized (standardized and replicable) Alcoholics Anonymous and similar 12-step facilitation programs produce higher rates of continuous abstinence than other established treatments.

    Structural MRI for the Early Diagnosis of Alzheimer Disease in Patients with MCI

    Erik Butler, Anne Mounsey

    There is insufficient evidence to recommend structural brain magnetic resonance imaging to diagnose Alzheimer disease in patients with mild cognitive impairment.

    Curbside Consultation

    Caring for the Physician Affected by Substance Use Disorder

    Ruchi M. Fitzgerald

    A 34-year-old physician, H.M., is an established patient in my practice. H.M. presents for a follow-up visit after finishing inpatient treatment for opioid use disorder.

    Photo Quiz

    Erosions and Vesicles in a Febrile Infant

    Michael Kim, Andrew Gaillardetz

    A five-month-old child with a history of dry skin presented with a spreading rash and fever.

    FPIN's Clinical Inquiries

    Platelet-Rich Plasma vs. Corticosteroids for Refractory Plantar Fasciitis

    Brian Atkinson, Katherine Holland Walker, Sue Stigleman, Aaron Vaughan, Stephen Hulkower

    Platelet-rich plasma injections are similar to corticosteroids for pain relief and improvement in function in patients with refractory plantar fasciitis lasting less than 12 weeks.

    Diagnostic Tests

    Serum Lactate Testing to Predict Mortality in Patients with Sepsis

    Kiana Espinosa, Steven R. Brown

    Management of patients with sepsis is challenging and mortality is high. Early diagnosis and prompt initiation of therapy are essential. Higher lactate levels correlate with increased risk of mortality, particularly with lactate levels greater than 4.0 mmol per L and in the...


    Bone Mineral Density Testing: One and Done

    Allen F. Shaughnessy

    Better Primary Care Continuity Is Associated with Lower Mortality Risk

    Henry C. Barry

    HPV Vaccine, Especially Before Age 17, Is Associated with a Large Reduction in Invasive Cervical Cancer

    Mark H. Ebell

    Low-Dose Edoxaban Effective for Stroke Prevention in Older Patients with Atrial Fibrillation

    Nita Shrikant Kulkarni

    Practice Guidelines

    Colonoscopy Follow-up: U.S. Multi-Society Task Force on Colorectal Cancer Updates Recommendations

    Brian Ford

    Screening colonoscopy findings define the future risk of colorectal cancer and the need for repeat screening. The U.S. Multi-Society Task Force on Colorectal Cancer updated recommended follow-up intervals after screening colonoscopy in average-risk individuals.

    Medicine by the Numbers

    Antiplatelet Agents for Preventing Early Recurrence of Ischemic Stroke or TIA

    Brit Long, Michael Gottlieb

    After atherothrombotic ischemic stroke or transient ischemic attack, adding clopidogrel to aspirin reduced recurrent strokes but increased major hemorrhages.

    Letters to the Editor

    Thoracic Outlet Syndrome Is Typically Not an Urgent Condition

    Douglas W. Martin

    Reply: Marc Childress

    Long-term Benefits of Manipulation for Neck Pain

    Brandon Isaacs

    Reply: Marc Childress

    An Osteopathic Approach to Neck Pain

    J. Christian Zona, Megan Cranor



    Incorrect statistics. In the article, “Breast Cancer Screening: Common Questions and Answers,” (January 1, 2021, p. 33), the figure listed for breast cancer deaths per number of women screened with mammography should have been per 10,000 women rather than per 100,000 women in...


    Incorrect Figure Legends. In the article, “Hip Pain in Adults: Evaluation and Differential Diagnosis,” (January 15, 2021, p. 81), the legend for Figure 3B incorrectly listed abducts instead of adducts. It should have read: “Flexion adduction internal rotation test. The...


    Incorrect Unit of Measure. In the article, “Eating Disorders in Primary Care: Diagnosis and Management,” (January 1, 2021, p. 22), the second sentence of the Nutrition section (page 25) incorrectly added “per kg” to the number of daily required kcal for adolescent females and...


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