Environment and Health

# 545 Edition | October 2024

Preface

As family physicians, we provide holistic care for our patients. Since the beginning of our specialty, we have recognized the ways that families and communities affect the physical, mental, and spiritual health of our patients. It is now becoming clear that we also need to consider the health implications of the environment, not just our patient’s genetic makeup, personal actions, and interactions with the people and systems around them.

In the 1960s, multiple high-profile environmental accidents increased public awareness of the risks of toxic exposures. On June 22, 1969, the Cuyahoga River in Cleveland, Ohio, spontaneously burst into flames after years of industrial waste being dumped into the river. In response to this environmental disaster and press coverage of it, President Richard Nixon proposed a comprehensive program to address pollution and study the effects of contaminants on the environment in 1970.1 This led to establishment of the Environmental Protection Agency (EPA), increased community awareness about the effects of pollution, and advancement of the scientific study of toxicology, environmental exposures, and occupational health.

For most patients, their family physician is their first point of contact with the health care system. Much of the time, identification of potential toxic exposures, initial testing and diagnosis, and patient education and risk reduction fall to primary care practices. Identification of toxic exposures is complicated. Determining the causative agent often involves awareness of group vulnerability and exposure risk as well as individual risk related to the location of the patient’s home, hobbies, or occupation. Family physicians should work with health departments and poison control centers to address individual patient exposures as well as public health concerns within the community. Physicians also need to be aware of reporting requirements for toxic exposures in their local jurisdictions.

This edition of FP Essentials addresses what family physicians need to know about the environment and health. Section One examines the roles of poison control centers, health departments, and family physicians in addressing toxic exposures. Section Two discusses heavy metal toxicity, including potential sources of exposure, symptoms of toxicity, and treatment of exposed patients. Section Three explores the causes and effects of water and soil contamination. Section Four reviews various endocrine-disrupting chemicals and their effects on health.

Although most of us received limited information about toxic substances as part of our medical education, we now encounter questions about exposures and their consequences for patient health on a regular basis. The information in this monograph will allow you to better guide your patients in this complex arena.

Ryan D. Kauffman, MD, FAAFP, CCFP, Associate Medical Editor
Family Medicine Physician
Erie Shores Family Health Team, Leamington, Ontario, Canada

References

  1. 1.Environmental Protection Agency. EPA history. The origins of EPA. https://www.epa.gov/history/origins-epa

Dhitinut (DT) Ratnapradipa, PhD, MPA, is a professor in the Department of Clinical Research and Public Health at Creighton University School of Medicine in Omaha, Nebraska. He also serves as program director for the master of public health program. Dr. Ratnapradipa has a secondary appointment in the Department of Family and Community Medicine. His area of focus is environmental health, and he previously served in state-level public health where he managed the state poison control program. Dr. Ratnapradipa served as clinical faculty at the Warren Alpert Medical School of Brown University in Providence, Rhode Island. He also served as graduate director and MD/MPH codirector of the concurrent degree program at Southern Illinois University School of Medicine in Springfield. He has authored more than 25 articles related to climate change and environmental and public health.

Amy L. McGaha, MD, MPH, FAAFP, is a professor in and chair of the Department of Family and Community Medicine at University of Nevada, Reno School of Medicine. Until recently, she was the Dr. Roland A. Kleeberger Endowed Chair of the Department of Family and Community Medicine at Creighton University School of Medicine. Dr. McGaha has served on the American Academy of Family Physicians (AAFP) Commission on Education and the Accreditation Council for Graduate Medical Education (ACGME) Family Medicine Milestones work group, which developed the first version of milestones for family medicine residency training. She has authored more than 20 publications on clinical topics in family medicine and interprofessional education.

The authors acknowledge the following individuals who provided research assistance: Danielle Hotalling, Martha Koenig, Kurt Parker, Megan Piotrowski, and Natasha Ratnapradipa.

Disclosure: It is the policy of the AAFP that all individuals in a position to control CME content disclose any relationships with ineligible companies upon nomination/invitation of participation. Disclosure documents are reviewed for potential relevant financial relationships. If relevant financial relationships are identified, mitigation strategies are agreed to prior to confirmation of participation. Only those participants who had no relevant financial relationships or who agreed to an identified mitigation process prior to their participation were involved in this CME activity. All individuals in a position to control content for this activity have indicated they have no relevant financial relationships to disclose.

  • Counsel patients regarding appropriate use of poison control centers.
  • Counsel patients about the role of the local health department in preventing and addressing exposures to toxic substances.
  • Recommend strategies for patients to avoid exposure to heavy metals.
  • Determine which patients are at highest risk of heavy metal toxicity.
  • Summarize potential sources of water and soil contamination.
  • Describe organophosphate poisoning.
  • Counsel patients about how to minimize exposure to endocrine-disrupting chemicals.
  • Summarize the effects of various endocrine-disrupting chemicals in the body.

Key Practice Recommendations

Sections

Poisoning Management

Poisoning is the leading cause of death due to unintentional injury in the United States. Each year, between 2,000,000 and 4,000,000 US poison exposures occur. Poison control centers (PCCs), health departments, and family physicians work at different levels of the health care…

Heavy Metal Toxicity

Heavy metals are naturally occurring, high-density elements such as arsenic, cadmium, chromium, lead, and mercury. These five metals are the most common causes of heavy metal poisonings. Zinc is also of concern. Heavy metals are widely distributed in the environment and can be…

Water and Soil Contamination

Exposures to pollutants and contaminants can occur through water or soil, which can be contaminated naturally or through human activities. The toxicity and adverse health effects of these substances depend on exposure route, quantity, and duration. Mechanisms of water…

Endocrine-Disrupting Chemicals

Endocrine-disrupting chemicals (EDCs) increasingly have been a subject of concern and study in the past few decades. These chemicals can interfere directly or indirectly with normal physiology of endocrine system organs or organs under the influence of hormones. EDCs have been…

  1. 1.Agency for Toxic Substances and Disease Registry, Centers for Disease Control and Prevention. https://www.atsdr.cdc.gov
  2. 2.Agency for Toxic Substances and Disease Registry, Centers for Disease Control and Prevention. Taking an exposure history. https://www.atsdr.cdc.gov/csem/exphistory/docs/CSEMExposHist-26-29.pdf
  3. 3.Agency for Toxic Substances and Disease Registry, Centers for Disease Control and Prevention. ToxGuides. https://wwwn.cdc.gov/TSP/ToxGuides/ToxGuidesLanding.aspx
  4. 4.American Academy of Pediatrics. Lead exposure. https://www.aap.org/en/patient-care/lead-exposure/
  5. 5.Darbre PD, ed. Endocrine Disruption and Human Health. 2nd ed. Elsevier; 2021.
  6. 6.Dignam T, Kaufmann RB, LeStourgeon L, Brown MJ. Control of lead sources in the United States, 1970-2017: Public health progress and current challenges to eliminating lead exposure. J Public Health Manag Pract. 2019;25(Suppl 1 Lead Poisoning Prevention):S13-S22.
  7. 7.Endoscreen. https://endoscreen.org/resources
  8. 8.Environmental Protection Agency. Search for Superfund sites where you live. https://www.epa.gov/superfund/search-superfund-sites-where-you-live
  9. 9.Frumkin H, ed. Environmental Health: From Global to Local. 3rd ed. Wiley; 2016.
  10. 10.Holtcamp W. Obesogens: an environmental link to obesity. Environ Health Perspect. 2012;120(2):a62-a68.
  11. 11.March of Dimes. https://www.marchofdimes.org
  12. 12.Myers S, Frumkin H. Planetary Health: Protecting Nature to Protect Ourselves. MyersSFrumkinH. Planetary Health: Protecting Nature to Protect Ourselves. Island Press; 2020.
  13. 13.National Capital Poison Center. The Poison Post. https://www.poison.org/the-poison-post
  14. 14.National Institute of Environmental Health Sciences. https://www.niehs.nih.gov/health
  15. 15.Natural Resources Defense Council. https://www.nrdc.org
  16. 16.Organization of Teratology Information Specialists. MothertoBaby. https://www.mothertobaby.org

Disclosure
All editors in a position to control content for this activity, FP Essentials, are required to disclose any relevant financial relationships. View disclosures.