Brian Veauthier, Michael V. Miller
Urinary tract infections (UTIs) are associated with significant short- and long-term morbidity in children. They have a high recurrence rate and are associated with anatomic and functional abnormalities. The decision to test for UTI is based on risk factors and the child's...
John M. Wilkinson, Magnus Halland
Esophageal motility disorders can cause chest pain, heartburn, or dysphagia. They are diagnosed based on esophageal manometry findings ranging from the complete absence of contractility in patients with achalasia to unusually forceful contractions in those with...
Ravi Kant, Amanda Davis, Vipin Verma
Thyroid nodules are typically benign and are often discovered incidentally. The primary goal of the evaluation is to determine whether the nodule is malignant. After performing thyroid ultrasonography, serum thyroid-stimulating hormone (TSH) should be measured. If levels are...
Steven Teutsch, Timothy S. Carey, Michael Pignone
Groups that are least likely to receive preventive screening or to have timely, high-quality follow-up include those with limited or no health insurance, limited education and literacy, and no regular source of care, as well as those who are subject to discrimination based on...
Key clinical questions and their evidence-based answers directly from the journal’s content, written by and for family physicians.
Steven R. Brown
Placental alpha macroglobulin-1 (PartoSure) is an immunoassay that measures the presence of placental alpha macroglobulin-1 (PAMG-1). PartoSure is used to assess the risk of spontaneous preterm birth and may be a useful adjunct to determine which patients with threatened...
Madhavi Singh, Kristen Grine, Amy Hays
PPAR gamma agonists are probably effective in preventing recurrent stroke in people with previous stroke or TIA.
William E. Cayley, Jr.
For adults hospitalized with severe CAP, the use of corticosteroids may reduce the likelihood of mortality.
Justin Bailey, Joey Florence
A man with a history of COPD from long-term tobacco use presented to the ER with worsening shortness of breath over the past week.
Kristina Gracey, Stephen Martin, Jennifer Reidy
In public health emergencies such as the COVID-19 pandemic, some patients—especially older patients or those who have chronic health conditions—are confronted with treatment choices as they face life-threatening illness.
Previous guidelines suggested that levothyroxine treatment may be appropriate with hypothyroid symptoms or a TSH level exceeding 10 mIU per L based on limited evidence. A recent large trial in older adults suggests that treatment shows no benefit in many areas and possible harm.
Anh-Chi Do, Jon O. Neher, Sarah Safranek
Vaginal, oral, and sublingual misoprostol in single doses of 600 to 800 mcg are equally effective for promoting completed abortion in patients with an incomplete first-trimester spontaneous abortion.
John Conway, Benjamin W. Friedman
Learn more about the effect of aspirin therapy given within 48 hours of acute ischemic stroke in reducing the risk of death, dependence, or recurrent stroke, and the chance of complete recovery.
A urinary tract infection (or UTI for short) affects the kidneys, bladder, or urethra (the tube that carries urine out of the body). UTIs are more common in girls and uncircumcised boys. They usually happen when germs that live in the intestines get into the urethra.
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