• Articles

    Urinary Tract Infections in Young Children and Infants: Common Questions and Answers

    Brian Veauthier, Michael V. Miller

    Urinary tract infections (UTIs) are associated with significant short- and long-term morbidity in children. They have a high recurrence rate and are associated with anatomic and functional abnormalities. The decision to test for UTI is based on risk factors and the child's...

    Esophageal Motility Disorders

    John M. Wilkinson, Magnus Halland

    Esophageal motility disorders can cause chest pain, heartburn, or dysphagia. They are diagnosed based on esophageal manometry findings ranging from the complete absence of contractility in patients with achalasia to unusually forceful contractions in those with...

    Thyroid Nodules: Advances in Evaluation and Management

    Ravi Kant, Amanda Davis, Vipin Verma

    Thyroid nodules are typically benign and are often discovered incidentally. The primary goal of the evaluation is to determine whether the nodule is malignant. After performing thyroid ultrasonography, serum thyroid-stimulating hormone (TSH) should be measured. If levels are...


    Health Equity in Preventive Services: The Role of Primary Care

    Steven Teutsch, Timothy S. Carey, Michael Pignone

    Groups that are least likely to receive preventive screening or to have timely, high-quality follow-up include those with limited or no health insurance, limited education and literacy, and no regular source of care, as well as those who are subject to discrimination based on...

    AFP Clinical Answers

    Otitis Media, COVID-19 and Hydroxychloroquine, Postoperative Pulmonary Risk, Hidradenitis Suppurativa

    Key clinical questions and their evidence-based answers directly from the journal’s content, written by and for family physicians.

    Diagnostic Tests

    Placental Alpha Macroglobulin-1 (PartoSure) Immunoassay to Assess the Risk of Spontaneous Preterm Birth

    Steven R. Brown

    Placental alpha macroglobulin-1 (PartoSure) is an immunoassay that measures the presence of placental alpha macroglobulin-1 (PAMG-1). PartoSure is used to assess the risk of spontaneous preterm birth and may be a useful adjunct to determine which patients with threatened...

    Cochrane for Clinicians

    Effectiveness of PPAR Gamma Agonists in Preventing Recurrent Stroke and Other Vascular Events

    Madhavi Singh, Kristen Grine, Amy Hays

    PPAR gamma agonists are probably effective in preventing recurrent stroke in people with previous stroke or TIA.

    Corticosteroids for Hospitalized Patients with Community-Acquired Pneumonia

    William E. Cayley, Jr.

    For adults hospitalized with severe CAP, the use of corticosteroids may reduce the likelihood of mortality.

    Photo Quiz

    Cloudy Pleural Fluid on Thoracentesis

    Justin Bailey, Joey Florence

    A man with a history of COPD from long-term tobacco use presented to the ER with worsening shortness of breath over the past week.

    Curbside Consultation

    Palliative Care During Public Health Emergencies: Examples from the COVID-19 Pandemic

    Kristina Gracey, Stephen Martin, Jennifer Reidy

    In public health emergencies such as the COVID-19 pandemic, some patients—especially older patients or those who have chronic health conditions—are confronted with treatment choices as they face life-threatening illness.

    Practice Guidelines

    Treatment of Subclinical Hypothyroidism: BMJ Rapid Recommendation

    Natasha Pyzocha

    Previous guidelines suggested that levothyroxine treatment may be appropriate with hypothyroid symptoms or a TSH level exceeding 10 mIU per L based on limited evidence. A recent large trial in older adults suggests that treatment shows no benefit in many areas and possible harm.

    FPIN's Help Desk Answers

    Misoprostol Dosing for First-Trimester Abortion

    Anh-Chi Do, Jon O. Neher, Sarah Safranek

    Vaginal, oral, and sublingual misoprostol in single doses of 600 to 800 mcg are equally effective for promoting completed abortion in patients with an incomplete first-trimester spontaneous abortion.

    Medicine by the Numbers

    Aspirin After Acute Ischemic Stroke

    John Conway, Benjamin W. Friedman

    Learn more about the effect of aspirin therapy given within 48 hours of acute ischemic stroke in reducing the risk of death, dependence, or recurrent stroke, and the chance of complete recovery.

    Letters to the Editor

    We're Listening and Taking Action on Racism and Health Inequities

    Sumi Sexton

    Information from Your Family Doctor

    UTIs in Children: What to Expect

    A urinary tract infection (or UTI for short) affects the kidneys, bladder, or urethra (the tube that carries urine out of the body). UTIs are more common in girls and uncircumcised boys. They usually happen when germs that live in the intestines get into the urethra.


    All editors in a position to control content for this activity, AFP journal, are required to disclose any relevant financial relationships. View disclosures.

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