brand logo

Am Fam Physician. 2021;104(2):137

What vitamins and supplements are recommended in pregnancy?

Prenatal vitamins for pregnant patients should contain folic acid, vitamin D, calcium, and iron. Pregnant patients should be counseled on the option to consume two or three servings per week of fish that contains low levels of mercury instead of routinely taking a fish oil supplement.

Which muscles should be targeted for strengthening when patellofemoral pain syndrome is present?

The American Physical Therapy Association recommends exercises that target muscles of the posterior hip and quadriceps for patellofemoral pain syndrome. Adding patellar taping and foot orthoses to exercise also improves short-term pain.

What are the first-line pharmacologic treatment options for alcohol use disorder?

Acamprosate and naltrexone should be used as first-line agents for the treatment of alcohol use disorder and are effective for reducing relapse rates. Agent selection should be based on comorbid conditions and adherence to the dosing regimen. Combining the two agents may provide additional benefit early in treatment.

What is the recommended first-line imaging modality for inguinal hernias not evident on clinical examination?

Ultrasonography is the first-line imaging modality to diagnose suspected groin hernias not evident on clinical examination, with a sensitivity of 33% to 86% and specificity of 77% to 90%.

What are the first-line and adjunct pharmacologic therapies used for anaphylaxis?

Administer intramuscular epinephrine into the anterolateral thigh as the first-line treatment of anaphylaxis. Use histamine H1 and H2 antagonists and corticosteroids only as adjunct therapies after the administration of epinephrine. Use fluid resuscitation (1 to 2 L of 0.9% isotonic saline at a rate of 5 to 10 mL per kg for adults in the first five to 10 minutes; 10 mL per kg for children) in patients who are anaphylactic with hypotension that does not improve with epinephrine.

Which medications are recommended for treating acute gout?

Nonsteroidal anti-inflammatory drugs and corticosteroids are equally effective for the treatment of acute gout, with no significant difference in pain relief or adverse effects. Low-dose colchicine (1.2 mg orally followed by 0.6 mg one hour later) is as effective as high-dose colchicine (1.2 mg followed by 0.6 mg every hour for six hours) with fewer adverse effects.

Additional Online Only AFP Clinical Answers

What are the treatment goals for children with ADHD?

Psychosocial interventions should be the first-line treatment in preschool children four to five years of age. Children who are six years and older can be offered stimulant medications for first-line treatment, with psychosocial interventions offered as an adjunct.

What initial treatment is recommended for patients with a mechanical globe injury?

Patients with a suspected mechanical globe injury should have a metal shield placed over the eye, be given antiemetics, and be referred immediately to an ophthalmologist for surgical repair. Prophylactic systemic antibiotics should be administered to prevent endophthalmitis.

How should patients with vulvar lichen sclerosus be treated?

Biopsy is indicated for patients with suspected lichen sclerosus because this condition is associated with an increased risk of squamous cell carcinoma. Patients should be treated with a high-potency steroid ointment to alleviate symptoms, prevent architectural damage, and reverse histologic changes.

Editor's Note: Several of the answers above first appeared in the new AFP Clinical Answers email, which is sent each month to recipients of the AFP email table of contents. Sign up to receive AFP emails.

Tip for Using AFP at the Point of Care

Looking for an algorithm? Go to the algorithm collection at You can search by keyword or sort by discipline or topic.

A collection of AFP Clinical Answers is available at

Continue Reading

More in AFP

Copyright © 2021 by the American Academy of Family Physicians.

This content is owned by the AAFP. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. This material may not otherwise be downloaded, copied, printed, stored, transmitted or reproduced in any medium, whether now known or later invented, except as authorized in writing by the AAFP.  See permissions for copyright questions and/or permission requests.