Articles
Low-Carbohydrate Diets
Low-carbohydrate diets induce greater weight loss at three and six months than traditional low-fat diets. However, there is no significant difference in maintained weight loss after one year.
Nonpharmacologic Strategies for Managing Hypertension
All patients with hypertension or prehypertension should undertake lifestyle modifications to help lower their blood pressure. These include reducing dietary sodium, increasing exercise, moderating alcohol consumption, following the Dietary Approaches to Stop Hypertension…
Nonalcoholic Fatty Liver Disease
Nonalcoholic fatty liver disease refers to a spectrum of diseases of the liver ranging from steatosis to nonalcoholic steatohepatitis to cirrhosis. Physicians should recommend regular exercise, gradual weight loss, and appropriate treatment of risk factors for cardiovascular…
Peripheral Vascular Disease: Diagnosis and Treatment
Most patients with peripheral vascular disease present with subtle findings and lack classic symptoms, which makes diagnosis difficult. Treatment may include lifestyle, medical, and surgical therapies.
Inborn Errors of Metabolism in Infancy and Early Childhood: An Update
Early and specific diagnosis of inborn errors of metabolism and prompt initiation of appropriate therapy are the best determinants of outcome for affected infants and children.
Inside AFP
Foundation of AFP is Its Medical Editors
The medical editors of AFP work as a team under the direction of Editor Jay Siwek, M.D., to bring together the best information for each issue. This final part of a three-part profile looks at four editors based in different parts of the country who contribute to the success of…
Newsletter
Newsletter
West Virginia and Kentucky Institute Medicaid Program Changes | Stable Formularies Guaranteed for Medicare Part D Beneficiaries | HHS Awards Contracts to Develop Cell-Based Influenza Vaccine | AHRQ Partners with Business Coalitions to Improve Diabetes Care | Annual Report…
Quantum Sufficit
Quantum Sufficit
People who see the glass as half full rather than half empty may be less likely to die from heart disease or stroke. According to a study in Archives of Internal Medicine, optimists may have this added benefit because they exercise more and can deal with misfortune better than…
Editorials
Low-Carbohydrate Dieting
Dieting is a national pastime in the United States, yet this preoccupation has done little to stem the tide of the obesity epidemic. In the past two decades, the prevalence of obesity in this country has doubled.1
Cochrane for Clinicians
Antidepressants for the Treatment of Neuropathic Pain
Tricyclic antidepressants, particularly amitriptyline, are effective for the treatment of painful diabetic neuropathy and post herpetic neuralgia, and may be beneficial in other neuropathic pain syndromes, but they should be used with caution in patients at increased risk of…
Pharmacologic Treatment of Psychotic Depression
An antidepressant such as imipramine (Tofranil) or sertraline (Zoloft), possibly with the addition of an antipsychotic, is the preferred initial pharmacologic treatment for psychotic depression.
Long-Acting Beta2 Agonists as Steroid-Sparing Agents
Long-Acting Beta2 Agonists as Steroid-Sparing Agents
U.S. Preventive Services Task Force
Screening for Developmental Dysplasia of the Hip: Recommendation Statement
This statement summarizes the U.S. Preventive Services Task Force (USPSTF) recommendations on screening for developmental dysplasia of the hip (DDH) and the supporting scientific evidence.
Clinical Evidence Handbook
Depressive Disorders
What are the effects of treatments in mild to moderate or severe depression? Which interventions reduce relapse rates? What are the effects of interventions to improve delivery of treatments?
FPIN's Clinical Inquiries
Warfarin for Prevention of Ischemic Stroke Recurrence?
There is no evidence that anticoagulation with warfarin, initiated after a noncardioembolic ischemic stroke, significantly reduces stroke recurrence. Furthermore, anticoagulation significantly increases the risk of fatal and nonfatal hemorrhagic stroke and extracranial…
Photo Quiz
Newborn with Abnormal Arm Posture
Photo Quiz presents readers with a clinical challenge based on a photograph or other image.
POEMs
Rimonabant Is Minimally Effective for Weight Loss
Low-Carb Diets Are Equal to Low-Fat Diets for Weight Loss
Duloxetine Is Effective for Fibromyalgia in Some Women
Three Major Statins Have Equivalent Effectiveness
Tips from Other Journals
Yoga Improves Chronic Low Back Pain
Reducing Inappropriate Antibiotic Prescriptions
Reducing Inappropriate Antibiotic Prescriptions
Severe Exacerbations of Asthma During Pregnancy
Positive and Negative Effects of Hypnotics in Older Patients
Pertussis Vaccination for Adolescents and Adults
Waist-to-Hip Ratio Better Predictor of Disease Than BMI
Intervention to Increase Breastfeeding Rates
Comparison of Effectiveness of Three CHD Predictors
Does Shared Decision Making Decrease Antibiotic Use?
Relation of Vaginal Delivery to Urinary Incontinence
Curbside Consultation
Determining Prognoses for Patients with Terminal Illnesses
Physicians often overestimate a terminal patient's life expectancy.
Practice Guidelines
AAP Reports on Healthy Weight-Control Practices in Young Athletes
The American Academy of Pediatrics (AAP) has released recommendations on healthy weight-control behaviors in young athletes to address counseling issues that physicians may encounter in caring for these patients. Children and adolescents often are involved in sports in which…
Practice Guideline Briefs
Joint Position Statement on Obesity in Older Adults
The American Society for Nutrition (ASN), the North American Association for the Study of Obesity (NAASO), and the Obesity Society have issued a joint position statement that includes a review of concerns related to obesity in older persons and weight management guidelines for…
AAP Revised Recommendations for Examination of Infants for ROP
The American Academy of Pediatrics (AAP) has released a policy statement revising its 2001 statement on screening examination of premature infants for retinopathy of prematurity (ROP).
Letters to the Editor
Determining Ectopic Pregnancy Risk Using Progesterone Levels
Information from Your Family Doctor
Is a Low-Carbohydrate Diet Right for Me?
Foods get their calories from protein, fats, and carbohydrates. Most of the calories you eat come from carbohydrates and fats. Carbohydrates are starches and sugars, which are in foods like bread, pasta, and sweets. Low-carbohydrate diets (or low-carb diets, for short) cut down…
High Blood Pressure: What You Should Know
High blood pressure is when the pressure in your arteries is higher than it should be. If you have high blood pressure, you are more at risk of having a heart attack or a stroke. You also are more at risk of getting kidney disease and even of dying.
Nonalcoholic Fatty Liver Disease: What You Should Know
NAFLD is a buildup of fat in the liver. NAFLD can be harmless, but sometimes it may cause the liver to swell. It is a common condition that has many causes, including some drugs and genetic disorders. The most common causes of NAFLD are obesity, diabetes, and high cholesterol…
