May 2026

Foot and ankle injections are commonly performed by family physicians for the management of several musculoskeletal conditions. If symptoms persist despite conservative measures, injections may improve function and reduce pain. Ultrasound guidance improves accuracy of injection…

Skin and soft tissue infections are clinical diagnoses. They are classified as mild, moderate, or severe, depending on the structures involved and presence or absence of systemic symptoms. Treatment depends on severity and includes oral and intravenous antibiotics

Botulinum toxin injection offers predictable results, has few adverse effects, and is associated with high patient satisfaction. A review of facial anatomy, injection techniques, and complications for cosmetic botulinum toxin treatment, with a focus on glabellar lines, is…

Severe hypertension is defined as a blood pressure of 180/110 to 120 mm Hg or greater in the absence of new or worsening target organ damage. Multiple trials have shown no short-term benefit of treatment, which has been associated with increased risk of cardiovascular events…

Metabolic and bariatric surgery is an effective treatment for severe obesity, improves cardiometabolic risk factors, and reduces mortality. Family physicians play a key role in managing postoperative complications, nutritional deficiencies, and long-term effects on chronic…

Despite significant advances in prevention and treatment, approximately 1.2 million Americans live with HIV. New developments in the care of patients with HIV include updated screening strategies, expanded prevention and treatment options, and management recommendations for…

Acknowledging and Thanking AFP’s 2025 Peer Reviewers

Addressing vaccine misinformation requires family physicians to move upstream into advocacy spaces.

GP Evidence (https://www.gpevidence.org) is a free website designed primarily for family physicians. it offers summaries of the evidence behind treatments for common conditions.

In children with ASD, treatment with risperidone or aripiprazole for 3 months may reduce irritability, obsessive-compulsive symptoms, and inappropriate speech. There is insufficient evidence to determine whether these drugs are effective in adults.

In adults with acute renal colic, NSAIDs provide clinically meaningful pain relief at 30 minutes. NSAIDs also reduce the need for rescue analgesia within 1 hour

A 32-year-old man presented with a rash in his right axilla that had developed 7 days earlier.

A 74-year-old woman presented with changes in the color of her nails and skin that started 15 years earlier.

Physicians should counsel adults to avoid use of e-cigarettes, because they may increase the risk of asthma and COPD.

Reassurance is a multifaceted interaction between a physician and a concerned patient that can reduce fear, worry, and doubt about the etiology of symptoms or possibility of a serious medical condition; reassurance results in positive changes in patient perception…

POEMs

POEMs

POEMs

POEMs

Pivmecillinam is well tolerated, but it is less conveniently dosed than other useful treatments for uncomplicated UTI. It may have a role in treatment of acute cystitis in patients where antibiotic resistance is a concern, but is too expensive for routine first-line use.

The American Academy of Pediatrics (AAP) published a clinical report of best practices based on expert opinion to guide physicians in differentiating child abuse from other causes.

The Centers for Disease Control and Prevention and Mycoses Study Group Education and Research Consortium released guidelines on when and how to test for fungal etiologies of pneumonia.

A color recommendation of yellow (unclear benefits) is assigned for interventions (eg, multifactorial interventions, active exercise, vitamin D supplementation) for reducing the rate of falls or fall risk in older people in care facilities.

Reply: Kamini Geer, MD, MPH, and Ann Klega, MD

Incorrect placement of table information. “Evaluation of Neck Masses in Adults” (February 2026, p. 160) incorrectly paired some diagnoses and supporting history and examination details for the physical examination finding “Diffuse cervical or more generalized lymphadenopathy…

Incorrect screening recommendation. “Cancer Screening in Older Adults” (December 2025, p. 629) incorrectly stated the age range for prostate cancer screening. Men should not be screened for prostate cancer after 69 years of age. The online version of the article has been…

Incorrect drug class. “Acute and Chronic Urticaria: Evaluation and Treatment” (March 2026, p. 222) incorrectly listed leukotriene receptor antagonists as leukotriene receptor agonists. The online version of the article has been corrected.

This funded, non-CME educational content was developed by Wiley with funding from BTL Industries, Inc. to provide convenient access to information that may be of interest. It should not be considered an AAFP or American Family Physician endorsement or recommendation of the…