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Photo Quiz

Blue-Gray Nails and Skin

Robert L. Gauer, MD
Daniel Blankinship, DO

American Family Physician. 2026;113(5):495-496.

Author disclosure: No relevant financial relationships.

ROBERT L. GAUER, MD, and DANIEL BLANKINSHIP, DO, Womack Army Medical Center, Fort Bragg, North Carolina

Address correspondence to Robert L. Gauer, MD, at robertgauer@yahoo.com.

Author disclosure: No relevant financial relationships.

  1. 1.Mota L, Dinis-Oliveira RJ. Clinical and forensic aspects of the different subtypes of argyria. J Clin Med. 2021;10(10):2086.
  2. 2.Beutler BD, Lee RA, Cohen PR. Localized cutaneous argyria: report of two patients and literature review. Dermatol Online J. 2016;22(11):13030/qt4wm1j7pt.
  3. 3.Lencastre A, Lobo M, João A. Argyria – case report. An Bras Dermatol. 2013;88(3):413-416.
  4. 4.Park SW, Shin HT, Lee KT, et al. Medical concern for colloidal silver supplementation: argyria of the nail and face. Ann Dermatol. 2013;25(1):111-112.
  5. 5.Molina-Hernandez AI, Diaz-Gonzalez JM, Saeb-Lima M, et al. Argyria after silver nitrate intake: case report and brief review of literature. Indian J Dermatol. 2015;60(5):520.
  6. 6.Mistry JB, Bukhari M, Taylor AM. Alkaptonuria. Rare Dis. 2013;1:e27475.
  7. 7.Girelli D, Busti F, Brissot P, et al. Hemochromatosis classification: update and recommendations by the BIOIRON Society. Blood. 2022;139(20):3018-3029.
  8. 8.Iolascon A, Bianchi P, Andolfo I, et al.; SWG of red cell and iron of EHA and EuroBloodNet. Recommendations for diagnosis and treatment of methemoglobinemia. Am J Hematol. 2021;96(12):1666-1678.
  9. 9.Schilsky ML, Roberts EA, Bronstein JM, et al. A multidisciplinary approach to the diagnosis and management of Wilson disease: 2022 practice guidance on Wilson disease from the American Association for the Study of Liver Diseases. Hepatology. 2025;82(3):E41-E90.

The editors of AFP welcome submissions for Photo Quiz. Guidelines for preparing and submitting a Photo Quiz manuscript can be found in the Authors' Guide at https://www.aafp.org/afp/photoquizinfo. To be considered for publication, submissions must meet these guidelines. Email submissions to afpphoto@aafp.org.

This series is coordinated by John E. Delzell Jr., MD, MSPH, associate medical editor.

A collection of Photo Quiz published in AFP is available at https://www.aafp.org/afp/photoquiz.

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