April 2026

Articles

Foreign Body Ingestion in Children

Christina Valerio, Ryan Williamson

Children commonly ingest foreign objects; prompt evaluation, imaging, and object-specific management may be necessary.

Thrombocytosis: Rapid Evidence Review

Pamela M. Williams, Alan L. Williams

Thrombocytosis is defined by guidelines as a platelet count of 450 × 103/μL or greater. Elevated platelet counts result from a primary condition or secondary cause. Secondary causes of thrombocytosis must be ruled out before a primary diagnosis may be made.

Vaccine Adverse Effects: An Overview

Sarah Coles

Family physicians should be aware of the risks and benefits of recommended immunizations to accurately counsel about adverse effects and address vaccine hesitancy.

Systemic Sclerosis: Evaluation and Treatment

Winfred Frazier, Courtney Goettel, Parul Chaudhri

Systemic sclerosis is a rare autoimmune disease characterized by progressive skin fibrosis and associated with high morbidity. Early diagnosis is critical and requires a comprehensive, individualized approach.

CMEAlgUrologic

Bladder Pain Syndrome: Rapid Evidence Review

Fay Roepcke, Ashley E. Jones, Kerac N. Falk

Bladder pain syndrome is a chronic condition diagnosed by excluding other causes, with initial evaluation involving history, physical examination, urinalysis, and symptom diaries. Treatment starts with behavioral and lifestyle changes and may include medications or procedural…

Heat-Related Illnesses

Robert L. Gauer, Ryan McNutt, Kevon Bryan

Heat-related illnesses are largely preventable with acclimatization, hydration, risk-factor modification, and early recognition and treatment.

AFP Clinical Answers

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Cold Water Immersion, Bronchiolitis in Infants, Trigeminal Neuralgia, HIV Screening, Buprenorphine and OUD, Beta2 Agonists for Acute Bronchitis, Nasal Foreign Body

Key clinical questions and their evidence-based answers directly from the journal’s content, written by and for family physicians.

Editorials

Integrating Drinking Water Safety Into Routine Practice

Dominika Jegen

Safe drinking water is essential to human health, but it is often overlooked in routine clinical care. Family physicians are uniquely positioned to ask patients about their water sources and provide practical counseling.

Managing Anxiety and Depression Symptoms in Long COVID

Lindsey M. Knowles, Kristen M. O'Loughlin, Nicole L. Gentile, Tracy E. Herring

Adults with long COVID face increased risk for anxiety and depression due to complex factors and benefit from a trauma-informed biopsychosocial approach to screening, assessment, and treatment.

Graham Center Policy One-Pager

Graduate Medical Education Funding Does Not Flow to Primary Care Physician Production

Trenten L. Fenster, Jeongyoung Park, Alison N. Huffstetler, Michael Topmiller

In many parts of the US, there is only one primary care physician per 2,000 people. This shortage is expected to worsen in the next decade. Although the need for primary care physicians is clear, the relationship between graduate medical education spending and primary care…

Cochrane for Clinicians

HPV Vaccination of Adolescents: Factors That Influence Caregiver and Adolescent Views and Practices

Joseph R. Yancey, Kathleen Bybel

Factors that influence adolescents and caregivers worldwide regarding adolescent receipt of the HPV vaccination fit into one of eight broad themes: (1) biomedical knowledge; (2) perceptions of the risks and benefits of HPV vaccination; (3) views of other vaccines or vaccination…

Fall Prevention: Interventions for Older Adults in Care Facilities

Dongsheng Jiang, Juan Qiu

Multifactorial interventions not tailored to individual needs (ie, defined as two or more strategies based on general risk profiles) probably have little or no effect on fall rate and may only modestly reduce overall fall risk. In contrast, tailored interventions, which are…

FPIN's Clinical Inquiries

Beta Blockers to Improve Post-MI Outcomes in Patients Without HF

Wesley Roten, Anne Mounsey, Ryan Paulus

Given mixed evidence about beta blockers in post–myocardial infarction patients without heart failure, clinicians should continue to follow local practice recommendations.

FPIN's Help Desk Answers

Uterine Leiomyomas as a Risk Factor for Infertility

Scott Cordts, Ryan Luce, Rebeca Nieves

Patients with more than one untreated leiomyoma of any size may have decreased fertility as measured by rates of pregnancy and live birth.

Diary of a Family Physician

Diary of a Family Physician

Llewellyn Mensah, Vikash Pernenkil

First-person accounts from the front lines of family medicine.

Photo Quiz

Nail Abnormality With Vertical Streaks

Courtney Humphrey, Lydia Bothwell

A 49-year-old man had concerns about a nail abnormality.

Cervical Mass

Mark Luff, Sidra Siddiqui, Mary Peter

A 59-year-old postmenopausal woman presented for a routine gynecological examination.

Curbside Consultation

Vaccine Conversations: Meeting Patients Where They Are

Aisha Townes, Allen F. Shaughnessy

Family physicians are best able to guide patients regarding vaccination hesitancy; strategies for communication include respectful communication and motivational interviewing.

POEMs

Practice Guidelines

Resuscitation After Drowning in Children: Updated Guidelines From the AHA and AAP

Michael J. Arnold

The American Heart Association (AHA) and American Academy of Pediatrics (AAP) published updated guidelines for resuscitation after drowning.

Management of Chronic Constipation: Guidelines From the American Society of Colon and Rectal Surgeons

Michael J. Arnold

The American Society of Colon and Rectal Surgeons published guidelines for the management of chronic constipation.

Letters to the Editor

Comments About Evidence-Based Vasectomy

John Curington

Reply: James J. Arnold, David Villanueva, Jane Puntkatalee

Benefits vs Harms of More Intensive Systolic BP Targets

Brian McDaniel, Julia Jenkins

Reply: Mark Ebell, David Slawson

What Do Guidelines Say About First-Line Treatment of Acute Low Back Pain?

Scott L. Paradise, Jase A. Schossow

Reply: J. Scott Earwood, Nancy A. Doles

Corrections

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Corrections

Incorrect units. “DASH Diet for the Primary and Secondary Prevention of Cardiovascular Diseases” (Cochrane for Clinicians, February 2026, p. 127) included incorrect units from the Cochrane Review and subsequent incorrect conversions to conventional units in the Practice…

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Corrections

Incorrect formulation. “Menopause Management: When Hormone Therapy Is Appropriate” (Editorials, February 2026, p. 115) referred to the incorrect formulation of estradiol in Table 2. The online version of the article has been corrected.

CME Course Information

Evidence-based Medicine Toolkit

Strength of Recommendation Taxonomy

Advertising: Career Opportunities (PDF download)

Disclosures

All editors in a position to control content for this activity, AFP journal, are required to disclose any relevant financial relationships. View disclosures.

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