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Cochrane for Clinicians

HPV Vaccination of Adolescents: Factors That Influence Caregiver and Adolescent Views and Practices

Joseph R. Yancey, MD, MHA, MBA,
Kathleen Bybel, DO,
Carl R. Darnall Army Medical Center, Fort Hood, Texas

American Family Physician. 2026;113(4):323-324.

Author disclosure: No relevant financial relationships.

This clinical content conforms to AAFP criteria for CME.

Author disclosure: No relevant financial relationships.

  1. 1.Cooper S, Schmidt BM, Jama NA, et al. Factors that influence caregivers’ and adolescents’ views and practices regarding human papillomavirus (HPV) vaccination for adolescents: a qualitative evidence synthesis. Cochrane Database Syst Rev. 2025(4):CD013430.
  2. 2.Bergman H, Buckley BS, Villanueva G, et al. Comparison of different human papillomavirus (HPV) vaccine types and dose schedules for prevention of HPV-related disease in females and males. Cochrane Database Syst Rev. 2019(11):CD013479.
  3. 3.National Cancer Institute. Cancer trends progress report. April 2025. Accessed October 3, 2025. https://progressreport.cancer.gov/prevention/hpv_immunization#jump-links-field-healthy-people-2030-target
  4. 4.Centers for Disease Control and Prevention. SchoolVaxView publications and resources. Accessed October 3, 2025. https://www.cdc.gov/schoolvaxview/pubs-resources/index.html
  5. 5.Abdullahi LH, Kagina BM, Ndze VN, et al. Improving vaccination uptake among adolescents. Cochrane Database Syst Rev. 2020(1):CD011895.
  6. 6.Centers for Disease Control and Prevention. HPV vaccination. Published August 2024. Accessed October 3, 2025. https://www.cdc.gov/hpv/vaccines/
  7. 7.Dempsey AF, Pyrznawoski J, Lockhart S, et al. Effect of a health care professional communication training intervention on adolescent human papillomavirus vaccination: a cluster randomized clinical trial. JAMA Pediatr. 2018;172(5):e180016.

These are summaries of reviews from the Cochrane Library.

This series is coordinated by Corey D. Fogleman, MD, assistant medical editor.

A collection of Cochrane for Clinicians published in AFP is available at https://www.aafp.org/afp/cochrane.

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