July 2026

Atypical moles are associated with increased risk of melanoma and should prompt periodic, systematic skin examination. Management includes clinical assessment with dermoscopy, excisional biopsy, and postbiopsy monitoring.

Menstrual patterns are key indicators of overall health, and amenorrhea—primary or secondary—requires timely evaluation using a thorough history, physical examination, and targeted laboratory testing. Diagnostic evaluation is individualized to identify endocrine, metabolic, or…

American Family Physician has selected the winners of our fifth annual photo contest, recognizing one medical student and one family medicine resident for their creative submissions highlighting the role AFP plays in their medical education and training.

Climate change caused by humans continues to accelerate, causing more frequent and severe weather events. Physicians can play a pivotal role in managing environmental health risks, such as heat and air pollution, and counseling patients on plant-forward diets and active…

Knee pain is prevalent across age groups, commonly related to osteoarthritis in older adults and patellofemoral syndrome in younger adults. Assessment includes a detailed history, physical examination (inspection, palpation, range of motion, strength testing, and specialized…

The evaluation of patients presenting with eye pain should focus on identifying potentially emergent causes that require prompt evaluation and treatment. Most causes of eye pain can be diagnosed by history and physical examination, including functional and anatomic assessment.

Routine questionnaire-based screening in asymptomatic adults in primary care is not supported by evidence demonstrating improved patient-oriented outcomes.

Screening for depression provides health benefit for adolescents, adults (including those older than 65), and people who are pregnant or postpartum.

Routine questionnaire-based screening in asymptomatic adults in primary care is not supported by evidence demonstrating improved patient-oriented outcomes.

A color recommendation of yellow (unclear benefits) is assigned for the use of pharmacotherapy for cannabis use disorder.

Systemic corticosteroids probably reduce 28-day mortality for adults (18 years and older) hospitalized with sepsis. Furthermore, systemic corticosteroids may decrease length of hospitalization, probably reduce in-hospital mortality, and may reduce 90-day all-cause mortality for…

Invasive traditional percutaneous needling and noninvasive acupressure PC6 acupoint stimulation reduce postoperative nausea compared with sham interventions. Invasive and noninvasive PC6 acupoint stimulation reduce postoperative vomiting compared with sham interventions…

Having a language-access plan can help physicians advocate and care for patients who decline interpreter services.

A 14-year-old girl presented with a painless swelling in her neck that had started 3 months prior.

A 4-day-old female infant was brought to the clinic for evaluation of a blue nodule near her left eye.

Menopause is associated with a 2.19 times higher risk of metabolic dysfunction-associated steatotic liver disease, previously known as nonalcoholic fatty liver disease.

Tradipitant (Nereus) is a P/neurokinin-1 receptor antagonist labeled for the prevention of motion-induced vomiting in adults.

Does oral norethindrone reduce prolonged uterine bleeding related to etonogestrel implant use?

In children and adults with eczema, is bathing daily or weekly better?

Is surgery more effective than placebo surgery or referral for supervised exercise therapy in patients with shoulder impingement syndrome?

Is risk-based mammography noninferior to routine annual?

The USDA and HHS have released updated dietary guidelines, emphasizing nutrient-dense foods and limiting highly processed foods, refined carbohydrates, and added sugars.

Chronic spine pain is defined as back pain lasting 3 months or longer with pain on at least one-half of days in the past 6 months. Chronic low back pain has been estimated to affect 4% of adults ages 24 to 39 years and 20% of adults ages 20 to 59 years. Chronic low back and…

Reply: Tamara McGregor, MD; Heather Dalton, MD; Jared Morphew, MD

Letter to the Editor

Reply: Nailah Adams Morancie, MD, MS, CAQSM, FAAFP

Incorrect test information. “Colorectal Cancer Screening and Prevention” (September 2025, p. 278) incorrectly described details related to the US Food and Drug Administration's approval of a blood-based colorectal cancer screening test (Shield), inclusion of the test in…

Adult immunizations are a cornerstone of preventive care. Waning immunity, older age, chronic conditions and social determinants of health increase adults' susceptibility to vaccine-preventable diseases. However, recent national data show that only 23 percent of people 19 years…