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Medicine by the Numbers

Pharmacotherapy for Cannabis Use Disorder

Simone Ilia, DO
Joseph Young, MD

American Family Physician. 2026;114(1):19A-19B.

Author disclosure: No relevant financial relationships.

SIMONE ILIA, DO, University of Tennessee Health Science Center College of Medicine, Murfreesboro

JOSEPH YOUNG, MD, SSM Health/Saint Louis University School of Medicine, Saint Louis, Missouri

Address correspondence to Simone Ilia, DO, at simone.ilia@ascension.org.

Author disclosure: No relevant financial relationships.

  1. 1.Substance Abuse and Mental Health Services Administration. 2024 National Survey on Drug Use and Health (NSDUH) releases. Updated September 8, 2025. Accessed March 4, 2026. https://www.samhsa.gov/data/data-we-collect/nsduh-national-survey-drug-use-and-health/national-releases/2024
  2. 2.Spiga F, Parkhouse T, Tang VM, et al. Pharmacotherapies for cannabis use disorder. Cochrane Database Syst Rev. 2025(9):CD008940.
  3. 3.Cannabis Promotions. Cannabis stats 2026. June 8, 2026. Accessed June 10, 2026. https://cannabispromotions.com/stats/legalization-timeline
  4. 4.Leung J, Chan GCK, Hides L, et al. What is the prevalence and risk of cannabis use disorders among people who use cannabis? A systematic review and meta-analysis. Addict Behav. 2020;109:106479.
  5. 5.Diagnostic and Statistical Manual of Mental Disorders. 5th ed. American Psychiatric Association; 2014.

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This series is coordinated by Christopher W. Bunt, MD, AFP assistant medical editor, and the NNT Group.

A collection of Medicine by the Numbers published in AFP is available at https:// www.aafp.org/afp/mbtn.

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