February 1, 2011

First-line therapies for acute migraine headache include combination analgesics, nonsteroidal anti-inflammatory drugs, and triptans. Other classes of drugs may be effective as adjunctive or alternative therapy options, but opiates and barbiturates are generally discouraged…

Osteochondrosis includes several disorders of growing bones with symptoms that typically appear during early adolescence. Patients often present with pain and disability in the hip, knee, foot, elbow, or back. Initial treatment varies by disorder, but usually does not require…

Patients with an idiopathic venous thromboembolism are more likely to have a recurrence than those who had a provoked event. When determining the duration of anticoagulation therapy, focus has shifted from laboratory testing to assessing clinical factors, such as the location…

Despite Increase in Allowed Charges, AAFP says CMS Is Still Undervaluing Primary Care | Registration Open for Medicare, Medicaid EHR Incentive Programs | Food Safety Act Allows FDA to Proactively Prevent Foodborne Illness Outbreaks | Physicians Need Training on How to Examine…

Should We Treat Moderately Elevated Triglycerides?Yes: Treatment of Moderately Elevated Triglycerides Is Supported by the Evidence

Should We Treat Moderately Elevated Triglycerides? No: Reducing Moderately Elevated Triglycerides Is Not Proven to Improve Patient Outcomes

The personal side of medicine told from the patient's perspective. The patient's story is followed by commentary from a physician and a list of resources.

For the management of incomplete miscarriage, limited-quality evidence shows that medical treatment with misoprostol (Cytotec), expectant care, and surgical evacuation have a completion of miscarriage success rate between 80 to 99 percent in pregnancies at less than 13 weeks…

Although further trials are needed, there is some evidence that clozapine is slightly more effective than risperidone (Risperdal). Fewer participants taking clozapine dropped out of studies because of lack of effectiveness compared with those taking risperidone (number needed…

Photo Quiz presents readers with a clinical challenge based on a photograph or other image.

Each year the Advisory Committee on Immunization Practices (ACIP) of the Centers for Disease Control and Prevention updates the recommended immunization schedules for children, adolescents, and adults. These schedules describe the immunizations recommended for routine…

Venous thromboembolism, or VTE, happens when a blood clot forms in a large vein deep in your body. This clot is called a deep venous thrombosis. It usually happens in the leg, causing pain, swelling, and redness. If the blood clot forms in your lungs, or if part of a blood clot…