May 1, 2019

Interventional radiology employs image guidance to perform diagnostic and treatment procedures. Interventional radiology techniques are effective, lower-risk alternatives to surgery for central venous catheter and port placement; for managing many sources of hemorrhage; and for…

Drug-drug interactions are common, and the identification of these interactions is essential to patient safety. Strategies for reducing the interactions include minimizing the number of drugs prescribed, regularly evaluating drug therapy, consideration of nonpharmacologic…

The annual installment of this series summarizes the top studies of 2018. These studies were summarized as POEMs (patient-oriented evidence that matters) and were highly rated by Canadian Medical Association members for their clinical relevance and expected health benefits to…

After having one year as editor-in-chief under my belt, I can say it has been an exciting challenge and a year of professional and personal growth. The purpose of this editorial is to welcome the first Jay Siwek medical editing fellow, share new journal features, highlight the…

Key clinical questions and their evidence-based answers directly from the journal’s content, written by and for family physicians.

asal saline irrigation reduces the severity of allergy symptoms for up to eight weeks vs. no treatment. It is uncertain if adding nasal saline to pharmacologic treatment further improves symptoms over pharmacologic treatment alone.

When treated with letrozole, subfertile women with PCOS who are trying to conceive have increased chances of pregnancy (number needed to treat [NNT] = 11) and live birth (NNT = 10) compared with those treated with clomiphene.

A five-year-old presented with numerous small erythematous plaques throughout her body but sparing the palms and soles. Treatment with topical antibiotic cream was unsuccessful.

What are the benefits and harms of psychotherapies and pharmacologic agents for the treatment of adults with posttraumatic stress disorder (PTSD)?

Using the INTERCHEST chest pain decision rule to decide next steps when a patient presents to a primary care physician with chest pain.

Elective labor induction at 39 weeks’ gestation leads to a mean 145-g (5.1-oz) lower birth weight compared with expectant management, but there is conflicting evidence about the effects on rates of cesarean delivery, perinatal mortality, operative vaginal birth, and admission…

The American College of Cardiology/American Heart Association (ACC/AHA) task force on clinical practice guidelines has updated its 2013 cholesterol guideline.

Denosumab appears to be effective in reducing the risk of vertebral and nonvertebral fractures in postmenopausal women with osteoporosis. Treatment with denosumab does not increase the risk of cancer or death but might increase the risk of infection. However, more studies are…