FPIN's Clinical Inquiries
From the Family Practice Inquiries Network

Weight Loss in Patients With Overweight or Obesity and Knee Osteoarthritis

Thomas Troy, MD
Hanh Ngo, MD
Lauren Pham, DO

American Family Physician. 2024;110(6):641-642.

Author disclosure: No relevant financial relationships.

THOMAS TROY, MD; HANH NGO, MD; and LAUREN PHAM, DO, University of Utah, Salt Lake City

Copyright © Family Physicians Inquiries Network. Used with permission.

Address correspondence to Thomas Troy, MD, at Tommy.Troy@hsc.utah.edu.

Author disclosure: No relevant financial relationships.

  1. 1.Christensen R, Bartels EM, Astrup A, et al. Effect of weight reduction in obese patients diagnosed with knee osteoarthritis: a systematic review and meta-analysis. Ann Rheum Dis. 2007;66(4):433-439.
  2. 2.Messier SP, Resnik AE, Beavers DP, et al. Intentional weight loss in overweight and obese patients with knee osteoarthritis: is more better? Arthritis Care Res (Hoboken). 2018;70(11):1569-1575.
  3. 3.Kolasinski SL, Neogi T, Hochberg MC, et al. 2019 American College of Rheumatology/Arthritis Foundation guideline for the management of osteoarthritis of the hand, hip, and knee. Arthritis Care Res (Hoboken). 2020;72(2):149-162.
  4. 4.American Academy of Orthopaedic Surgeons. Management of osteoarthritis of the knee (non-arthroplasty): evidence-based clinical practice guideline; August 31, 2021. Accessed October 21, 2024. https://www.aaos.org/oak3cpg

Clinical Inquiries provides answers to questions submitted by practicing family physicians to the Family Physicians Inquiries Network (FPIN). Members of the network select questions based on their relevance to family medicine. Answers are drawn from an approved set of evidence-based resources and undergo peer review. The strength of recommendations and the level of evidence for individual studies are rated using criteria developed by the Evidence-Based Medicine Working Group (https://www.cebm.net).

The complete database of evidence-based questions and answers is copyrighted by FPIN. If interested in submitting questions or writing answers for this series, go to https://www.fpin.org or email questions@fpin.org.

Copyright © Family Physicians Inquiries Network. Used with permission.

This series is coordinated by John E. Delzell Jr., MD, MSPH, associate medical editor.

A collection of FPIN’s Clinical Inquiries published in AFP is available at https://www.aafp.org/afp/fpin.

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