• Articles

    Practical Selection of Antiemetics in the Ambulatory Setting

    ZACHARY A. FLAKE, BECKY S. LINN, JAIME R. HORNECKER

    Clinicians can improve the effectiveness and cost-effectiveness of antiemetics by targeting the appropriate neurotransmitter pathway that mediates nausea and vomiting. Antihistamines and anticholinergics are most effective in patients with vestibular-mediated nausea secondary...

    Diagnosis and Management of Sodium Disorders: Hyponatremia and Hypernatremia

    MICHAEL M. BRAUN, CRAIG H. BARSTOW, NATASHA J. PYZOCHA

    Plasma osmolality plays a critical role in the treatment of sodium disorders. Hyponatremia and hypernatremia are classified based on volume status. Sodium disorders are diagnosed by findings from the history, physical examination, laboratory studies, and evaluation of volume...

    Evaluation and Treatment of Infertility

    TAMMY J. LINDSAY, KIRSTEN R. VITRIKAS

    Evaluation of infertility should be offered to couples who have not conceived after 12 months of regular, unprotected vaginal intercourse. In addition to a history and physical examination, men should undergo a semen analysis, and women should be assessed for ovulation...

    AAFP News: AFP Edition

    AAFP News: AFP Edition

    CMS to Revise Meaningful Use in 2015 | HHS Lays Out Path to Move Away From Fee-for-Service Medicare Payment | Studies Point to Recent Slowdown in Opioid Abuse, but Work Remains | AAFP Warns That EHR Certification Methods Fail Physicians, Patients

    Cochrane for Clinicians

    Controlled-Release Oxycodone for Neuropathic Pain and Fibromyalgia in Adults

    MEGHAN F. RALEIGH, ANGELA M. DUNN

    Oxycodone CR has limited effectiveness for the treatment of diabetic neuropathy or postherpetic neuralgia. Evidence is lacking regarding treatment benefit for other neuropathic pain syndromes or fibromyalgia. Adverse effects of oxycodone CR therapy are common.

    Risk of Venous Thromboembolism with Use of Combined Oral Contraceptives

    AARON SAGUIL

    All combined oral contraceptives increase VTE risk. The risk is greater for those containing desogestrel, drospirenone, gestodene (not available in the United States), and cyproterone acetate (not available in the United States) when compared with levonorgestrel. All combined...

    Editorials

    Improving Quality by Doing Less: Overtreatment

    JESSICA HERZSTEIN, MARK EBELL

    The third in a series of AFP editorials that addresses the related issues of over-screening, overdiagnosis, and overtreatment. Overtreatment is an important harm that commonly follows overscreening and overdiagnosis.

    FPIN's Clinical Inquiries

    Obesity and Joint Injuries in Children

    BRYAN A. SUNDIN, ELIZABETH MORENO, JON O. NEHER, LEILANI ST. ANNA

    Lower extremity injuries are 18% more likely in overweight children, 24% more likely in obese children, and 34% more likely in extremely obese children when compared with normal weight peers. The risk of lower extremity fractures is also increased by 17% in overweight...

    Photo Quiz

    Blisters Over the Buttocks

    PURNIMA BANSAL, BODE ADEBAMBO

    A 7-year-old girl with a history of pain in her lower abdomen and buttocks developed multiple bullous lesions in the perirectal area involving the gluteal cleft and both buttocks.

    STEPS

    Vortioxetine (Brintellix) for the Treatment of Depression

    MEGAN K. MAGOVERN, KATHARINE C. DEGEORGE

    Current evidence does not support the routine use of vortioxetine in the treatment of depression. Family physicians most often encounter patients with mild to moderate depression, and vortioxetine has not been studied in this population. There is no clear benefit of using...

    POEMs

    Lung Cancer Screening Is Cost-Effective, but Only If Done Correctly

    MARK H. EBELL

    The U.S. Preventive Services Task Force (USPSTF) gave lung cancer screening a B recommendation on the basis of the reductions in disease-specific mortality and all-cause mortality seen in the National Lung Screening Trial (NLST). The NLST does not consider cost or cost...

    Practice Guidelines

    AHA/ASA Release Guideline on Stroke Prevention in Women

    AMBER RANDEL

    The American Heart Association and American Stroke Association (AHA/ASA) have released a guideline to help physicians identify women with increased risk of stroke and initiate appropriate preventive measures. The guideline includes recommendations on pregnancy and stroke;...

    U.S. Preventive Services Task Force

    Low-Dose Aspirin Use for the Prevention of Morbidity and Mortality from Preeclampsia: Recommendation Statement

    The U.S. Preventive Services Task Force (USPSTF) recommends the use of low-dose aspirin (81 mg per day) as preventive medication after 12 weeks of gestation in women who are at high risk of preeclampsia.

    Primary Care Behavioral Interventions to Reduce Illicit Drug and Nonmedical Pharmaceutical Use in Children and Adolescents: Recommendation Statement

    The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of primary care–based behavioral interventions to prevent or reduce illicit drug or nonmedical pharmaceutical use in children and adolescents. This recommendation...

    Letters to the Editor

    Cancer Risk Should Prompt Hepatitis B Surveillance for Patients

    SEIJI YAMADA

    Lidocaine Is an Option for Treating Postmenopausal Dyspareunia

    KRISTIN K. ELLIOTT

    Information from Your Family Doctor

    Infertility: What Women Should Know

    Infertility is defined as not being able to get pregnant after 12 months of trying. It may be caused by medical problems in you or your partner. In about 40% of cases, there are factors in both partners. About 25% of couples do not have a clear reason for their infertility....



    Disclosure

    All editors in a position to control content for this activity, AFP journal, are required to disclose any relevant financial relationships. View disclosures.


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