ZACHARY A. FLAKE, BECKY S. LINN, JAIME R. HORNECKER
Clinicians can improve the effectiveness and cost-effectiveness of antiemetics by targeting the appropriate neurotransmitter pathway that mediates nausea and vomiting. Antihistamines and anticholinergics are most effective in patients with vestibular-mediated nausea secondary...
MICHAEL M. BRAUN, CRAIG H. BARSTOW, NATASHA J. PYZOCHA
Plasma osmolality plays a critical role in the treatment of sodium disorders. Hyponatremia and hypernatremia are classified based on volume status. Sodium disorders are diagnosed by findings from the history, physical examination, laboratory studies, and evaluation of volume...
TAMMY J. LINDSAY, KIRSTEN R. VITRIKAS
Evaluation of infertility should be offered to couples who have not conceived after 12 months of regular, unprotected vaginal intercourse. In addition to a history and physical examination, men should undergo a semen analysis, and women should be assessed for ovulation...
CMS to Revise Meaningful Use in 2015 | HHS Lays Out Path to Move Away From Fee-for-Service Medicare Payment | Studies Point to Recent Slowdown in Opioid Abuse, but Work Remains | AAFP Warns That EHR Certification Methods Fail Physicians, Patients
MEGHAN F. RALEIGH, ANGELA M. DUNN
Oxycodone CR has limited effectiveness for the treatment of diabetic neuropathy or postherpetic neuralgia. Evidence is lacking regarding treatment benefit for other neuropathic pain syndromes or fibromyalgia. Adverse effects of oxycodone CR therapy are common.
All combined oral contraceptives increase VTE risk. The risk is greater for those containing desogestrel, drospirenone, gestodene (not available in the United States), and cyproterone acetate (not available in the United States) when compared with levonorgestrel. All combined...
JESSICA HERZSTEIN, MARK EBELL
The third in a series of AFP editorials that addresses the related issues of over-screening, overdiagnosis, and overtreatment. Overtreatment is an important harm that commonly follows overscreening and overdiagnosis.
BRYAN A. SUNDIN, ELIZABETH MORENO, JON O. NEHER, LEILANI ST. ANNA
Lower extremity injuries are 18% more likely in overweight children, 24% more likely in obese children, and 34% more likely in extremely obese children when compared with normal weight peers. The risk of lower extremity fractures is also increased by 17% in overweight...
PURNIMA BANSAL, BODE ADEBAMBO
A 7-year-old girl with a history of pain in her lower abdomen and buttocks developed multiple bullous lesions in the perirectal area involving the gluteal cleft and both buttocks.
MEGAN K. MAGOVERN, KATHARINE C. DEGEORGE
Current evidence does not support the routine use of vortioxetine in the treatment of depression. Family physicians most often encounter patients with mild to moderate depression, and vortioxetine has not been studied in this population. There is no clear benefit of using...
MARK H. EBELL
The U.S. Preventive Services Task Force (USPSTF) gave lung cancer screening a B recommendation on the basis of the reductions in disease-specific mortality and all-cause mortality seen in the National Lung Screening Trial (NLST). The NLST does not consider cost or cost...
The American Heart Association and American Stroke Association (AHA/ASA) have released a guideline to help physicians identify women with increased risk of stroke and initiate appropriate preventive measures. The guideline includes recommendations on pregnancy and stroke;...
The U.S. Preventive Services Task Force (USPSTF) recommends the use of low-dose aspirin (81 mg per day) as preventive medication after 12 weeks of gestation in women who are at high risk of preeclampsia.
The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of primary care–based behavioral interventions to prevent or reduce illicit drug or nonmedical pharmaceutical use in children and adolescents. This recommendation...
KRISTIN K. ELLIOTT
Infertility is defined as not being able to get pregnant after 12 months of trying. It may be caused by medical problems in you or your partner. In about 40% of cases, there are factors in both partners. About 25% of couples do not have a clear reason for their infertility....
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