ALLEN R. LAST, JONATHAN D. FERENCE, ELIZABETH ROLLMANN MENZEL
Guidelines from several major organizations recommend lipid-lowering therapy for primary and secondary prevention of atherosclerotic cardiovascular disease events in at-risk patients. Multiple risk calculators are available to determine a patient's 10-year risk of an event....
DUSTIN K. SMITH, SAJEEWANE SEALES, CAROL BUDZIK
Patients with bronchiolitis usually present with two to four days of upper respiratory tract symptoms followed by lower respiratory tract symptoms. Bronchiolitis is a clinical diagnosis, and diagnostic testing is not routinely recommended. Treatment is mainly supportive, and...
MARIA SYL D. DE LA CRUZ, EDWARD M. BUCHANAN
Uterine fibroids can cause significant symptoms, including abnormal bleeding, pelvic pressure, bowel and bladder dysfunction, low back pain, and dyspareunia. Ultrasonography is the preferred initial imaging modality. Expectant management is recommended for asymptomatic...
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Statins will long remain the cornerstone of treatment because of their proven benefits and cost-effectiveness, especially in the four statin benefit groups. However, emerging RCT evidence shows that the degree of LDL-C lowering may be more important than the drug used to...
RODERICK P. VENEKAMP, ROGER A.M.J. DAMOISEAUX, ANNE G.M. SCHILDER
What are the effects of treatments (analgesics, antibiotics, and myringotomy) in children with acute otitis media?
A man presented with right-sided neck, throat, and ear pain after a five-mile run.
BRIAN DAILY, PAUL DASSOW, JAMES HAYNES, JOAN NASHELSKY
Corticosteroid therapy in patients with suspected giant cell arteritis should not degrade the accuracy of temporal artery biopsy if the biopsy is performed within four weeks of corticosteroid initiation. Temporal artery biopsy can be performed up to four weeks after starting...
No single person can be responsible for the health of a population. However, there are a number of strategies for taking care of members of disadvantaged populations. These range from targeted compassion and interventions for the individual patient to broad advocacy for...
R. CHRISTOPHER DURIGAN, VALERIE NIEDERMIER
Umeclidinium is an easy-to-use, once-daily, well-tolerated, and relatively low-cost anti-cholinergic agent for maintenance therapy in patients with moderate to severe COPD.
For women with symptoms suggestive of endometriosis, serum CA 125 is a relatively specific (93%) and noninvasive test. It can be used to make a presumptive diagnosis in cases for which a medical management approach is being considered without having to perform a (diagnostic...
MARK H. EBELL
Compared with usual care, the use of CPAP provides a modest improvement in daytime sleepiness, but does not reduce the likelihood of cardiovascular events, even in a high-risk population.
NITA SHRIKANT KULKARNI
The Centers for Disease Control and Prevention (CDC) first published the U.S. Selected Practice Recommendations for Contraceptive Use (U.S. SPR) in 2013 to provide direction for safe and effective use of contraceptive methods. These guidelines update the 2013 report.
The USPSTF recommends that adults without a history of cardiovascular disease (CVD) (i.e., symptomatic coronary artery disease or ischemic stroke) use a low- to moderate-dose statin for the prevention of CVD events and mortality when all of the following criteria are met: (1)...
Respiratory syncytial virus (RESS-per-uh-TOR-ee sin-SISH-uhl VIE-russ), or RSV, causes fever, stuffy or runny nose, sore throat, and cough. Your child is more likely to get RSV between November and April. Most children have had at least one RSV infection by two years of age....
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