• Articles

    Nutrition Support Therapy

    Mary N. R. Lesser, Lenard I. Lesser

    Nutrition support therapy is the delivery of formulated enteral or parenteral nutrients to maintain or restore nutrition status. Family physicians can provide nutrition support therapy to patients at risk of malnutrition when it would improve clinical outcomes or quality of...

    Septic Arthritis: Diagnosis and Treatment

    John Scott Earwood, Tyler R. Walker, Gregory J. C. Sue

    Physical examination findings and serum markers, including erythrocyte sedimentation rate and C-reactive protein, are helpful in the diagnosis of septic arthritis but are nonspecific. Synovial fluid studies are required to confirm the diagnosis. Antibiotic treatment should be...

    Cannabis Essentials: Tools for Clinical Practice

    Payam Sazegar

    Cannabis use in the United States is on the rise because of state-level legalization, decreased risk perception, and increased social acceptability. Cannabis use can impair short-term memory, judgment, and coordination. Treatment of cannabis use disorder is largely behavioral...

    Thyroiditis: Evaluation and Treatment

    Beatriz Martinez Quintero, Cynthia Yazbeck, Lori B. Sweeney

    Thyroiditis is a general term for inflammation of the thyroid gland. The most common forms of thyroiditis encountered by family physicians include Hashimoto disease, postpartum, and subacute. Most forms of thyroiditis result in a triphasic disease pattern of thyroid dysfunction.

    Community-Acquired Pneumonia in Children: Rapid Evidence Review

    Dustin K. Smith, Daniel P. Kuckel, Anthony M. Recidoro

    In the United States, pneumonia is the most common cause of hospitalization in children. Treatment is dependent on age, treatment setting, and vaccination status. Typical presenting signs and symptoms include tachypnea, cough, fever, and anorexia.

    Hepatitis C: Diagnosis and Management

    David L. Maness, Elly Riley, Grant Studebaker

    Hepatitis C virus infection is an underdiagnosed and undertreated multifaceted systemic disease that affects an estimated 3.7 million people in the United States. Globally, less than 5% of people with hepatitis C virus infection have been diagnosed, and less than 1% have...


    Translating the 2020–2025 U.S. Dietary Guidelines into Clinical Practice

    Amy B. Locke

    The answer to the simple question “What should we eat?” is remarkably contentious and fraught with strongly held personal beliefs and preferences, as well as substantial financial and disease implications. It is a question that patients and families often ask their physicians...

    Dismantling Anti-Black Racism in Medicine

    José E. Rodríguez, Kendall M. Campbell, Judy C. Washington

    The murders of George Floyd and countless other members of the Black community by police prompted family medicine journals and professional societies to publish antiracism statements that provide actions, plans, and accountability structures to eliminate systemic anti-Black...

    Is Artificial Intelligence the Key to Reclaiming Relationships in Primary Care?

    Winston Liaw, Ioannis A. Kakadiaris, Zhou Yang

    Over the past decade, artificial intelligence (i.e., technologies that perform tasks that normally require human intelligence) has been integrated into clinical decision support systems to provide timely information at the point of care and inform medical decision-making....

    Graham Center Policy One-Pagers

    Family Physicians Continue to Offer the Most Comprehensive Care

    Monica Ajinkya, Stephen Petterson, Jack Westfall, Yalda Jabbarpour

    Comprehensiveness of care is one of the cardinal attributes of high-performing primary care. Evidence has shown that more comprehensive care, as measured by the number of services offered, is associated with lower costs and a reduction in hospitalizations. Comprehensiveness...

    AFP Clinical Answers

    Tinnitus, HIV Infection, Joint Hypermobility Disorders, Drug-Resistant Epilepsy, Cancer Pain

    Key clinical questions and their evidence-based answers directly from the journal’s content, written by and for family physicians.

    Cochrane for Clinicians

    Single-Dose Oral NSAIDs and Acetaminophen for Perineal Pain in the Early Postpartum Period

    Tyler S. Rogers, Molly Chandler, Ashley Hall

    In patients with acute perineal pain at four hours' postpartum, a single dose of an oral NSAID and a single dose of oral acetaminophen are each effective at achieving adequate pain relief. Both NSAIDs and acetaminophen are effective at reducing the need for further analgesia....

    Trigger Finger: Safety and Effectiveness of NSAID vs. Steroid Injection Therapy

    Alan L. Williams, Jeffrey C. Leggit

    In patients with trigger finger, there is no significant difference in outcomes at 12 to 24 weeks— including resolution of symptoms, recurrence, total active motion, residual pain, patient satisfaction, or adverse events—when comparing treatment with NSAID injections vs....

    Point-of-Care Guides

    Neonatal Early-Onset Sepsis Calculator

    Kiana Espinosa, Steven R. Brown

    Can the neonatal early-onset sepsis calculator safely and accurately evaluate the risk of early-onset sepsis in neonates?

    FPIN's Clinical Inquiries

    Virtual Reality in the Treatment of Generalized Anxiety Disorder

    Morgan Hungenberg, Shawnecca Burke, Aline Hansen-Guzman, Shaun Thompson, Corey Lyon, Kristen DeSanto

    Virtual reality does not appear to be effective and should not be used in the treatment of generalized anxiety disorder. In trials including anxiety disorders such as phobias and fear of flying, virtual reality may be better than no treatment, but it is not superior to...

    Putting Prevention Into Practice

    Screening for Gestational Diabetes

    Justin Mills, Sopan Mohnot

    A 28-year-old South Asian patient at 30 weeks' gestation, S.F., presents to transfer prenatal care to your clinic. The patient has recently moved, and prenatal records indicate that S.F.'s most recent prenatal visit was at 22 weeks' gestation. This is the patient's first...

    Diary of a Family Physician

    Diary of a Family Physician

    Seiji Hayashi

    First-person accounts from the front lines of family medicine.

    Photo Quiz

    Green Toenail Discoloration

    Thomas Quattlebaum, Charles Sonido

    A woman presented with green discoloration of her right first toenail.

    Surfer with Photodistributed Erythematous, Scaling Eruption

    Shayna C. Rivard

    A surfer presents with a worsening rash with erythema and scaling after treatment with a topical medication.

    Lown Right Care

    Prediabetes Diagnosis: Helpful or Harmful?

    Andy Lazris, Alan R. Roth, Helen Haskell, John James

    A collaboration between AFP and the Lown Institute promotes a vision of delivering health care that is based on the evidence, balanced in its approach, and focused on the patient.

    Practice Guidelines

    Lyme Disease: Updated Recommendations from the IDSA, AAN, and ACR

    Alan L. Williams, Jeffrey Bevan, Michael J. Arnold

    A multidisciplinary panel representing the Infectious Diseases Society of America, the American Academy of Neurology, and the American College of Rheumatology has published recommendations on the prevention, diagnosis, and treatment of Lyme disease.

    Microscopic Hematuria in Adults: Updated Recommendations from the American Urological Association

    Michael J. Arnold

    The American Urological Association released an updated guideline for risk-based evaluation of microscopic hematuria.

    Medicine by the Numbers

    Probiotics for Preventing Antibiotic-Associated Diarrhea

    Brit Long, Michael Gottlieb

    Learn more about probiotics for preventing antibiotic-associated diarrhea.


    Third Pfizer Vaccine Dose Significantly Increases Protection Against Mild and Severe COVID-19 in Patients 60 Years and Older

    Mark H. Ebell

    A third booster dose of the Pfizer-BioNTech mRNA vaccine against COVID-19 provides a large increase in protection for people 60 years and older against mild and severe infection. The protection against mild infection could help reduce community spread and reduce the incidence...

    Some Nonpharmacologic Treatments May Decrease Migraine Frequency in Children and Adolescents

    Allen F. Shaughnessy

    Active nonpharmacologic treatments such as biofeedback, relaxation techniques, and general or specific psychological support (e.g., cognitive behavior therapy) may be a good place to start when trying to decrease migraine frequency in children and adolescents. The research is...

    Ultrasonography Is Accurate for Diagnosing Upper Extremity Fractures in Children

    Henry C. Barry

    Diagnostic ultrasonography is highly accurate for diagnosing most upper extremity fractures but slightly less accurate for fractures involving the elbow. Clinicians should not use ultrasonography alone to rule in elbow fractures in children.

    Left Atrial Appendage Occlusion During Cardiac Surgery for Another Reason Reduces the Risk of Stroke

    Mark H. Ebell

    Surgical closure of the left atrial appendage during cardiac surgery for another reason safely reduces the risk of ischemic stroke. Because the risk of stroke in the first 30 days after any cardiac surgery is approximately 2% and the absolute reduction in the risk of stroke...

    Letters to the Editor

    More Study Needed of Preferred Regimens for Medication Abortion Beyond 70 Days


    All editors in a position to control content for this activity, AFP journal, are required to disclose any relevant financial relationships. View disclosures.

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