• Articles

    Office-Based Urinalysis: A Comprehensive Review

    Nathan Hitzeman, Dineen Greer, Erik Carpio

    Urinalysis is a simple, inexpensive means of detecting urologic and systemic conditions such as infection, urolithiasis, malignancy, and metabolic diseases. Visual inspection of the urine, familiarity with dipstick testing, and point-of-care micros-copy are important...

    Celiac Disease: Common Questions and Answers

    Pamela M. Williams, Lisa M. Harris, Michael R. Odom

    Celiac disease may present with a variety of manifestations and develop at any age. This article presents evidence-based answers to common questions about the evaluation and management of celiac disease.

    Acute Pancreatitis: Rapid Evidence Review

    Kathryn E. Oppenlander, Christina Chadwick, Kayla Carman

    This article summarizes the best available patient-oriented evidence for the diagnosis and treatment of acute pancreatitis, the most common gastrointestinal condition requiring hospital admission in the United States.

    Care of the Active Female

    Katherine Wojnowich, Rachel Dhani

    Physical activity has many health-related benefits, including prevention and management of chronic disease, weight management, and improved mental health. Active females are at risk of overuse injuries; treatment of overuse injuries usually includes activity modification, a...

    Top 20 Research Studies of 2021 for Primary Care Physicians

    Mark H. Ebell, Roland Grad

    The annual installment of this series summarizes the top studies of 2021, which were summarized as POEMs (patient-oriented evidence that matters). Topics in this group of studies include type 2 diabetes mellitus, musculoskeletal conditions, gastrointestinal conditions, and...

    Acute Diarrhea in Adults

    Erica S. Meisenheimer, Carly Epstein, Derrick Thiel

    In the United States, diarrhea accounts for an estimated 179 million outpatient visits, 500,000 hospitalizations, and more than 5,000 deaths annually, resulting in approximately one episode of acute diarrheal illness per person per year. Infectious noninf lammatory diarrhea...


    Controversial Topics in Family Medicine and Our Duty to Engage

    Marc Tunzi, William Ventres, Philip G. Day, David J. Satin

    What are the ethical responsibilities for clinical journals publishing articles on controversial topics?

    Ethics, Education, and American Family Physician

    Sumi M. Sexton

    American Family Physician covers a comprehensive array of topics in family medicine.

    Medicine by the Numbers

    Membrane Sweeping at Term to Induce Labor

    Brian Ford, Andrew Anderson, Carrie Nichols

    Learn more about term membrane sweeping to induce labor.

    AFP Clinical Answers

    DVT, AAA, Sleep Apnea in Children, MODY, Fever, Sacroiliac Joint Dysfunction

    Key clinical questions and their evidence-based answers directly from the journal’s content, written by and for family physicians.

    Cochrane for Clinicians

    DPP-4 Inhibitors, GLP-1 Receptor Agonists, and SGLT-2 Inhibitors for People With Cardiovascular Disease

    Kento Sonoda, Aaron Saguil

    DPP-4 inhibitors do not reduce mortality or cardiovascular outcomes in people with CVD, and they increase the risk of pancreatitis. GLP-1 receptor agonists reduce cardiovascular mortality, all-cause mortality, and stroke in people with CVD. SGLT-2 inhibitors reduce...

    Palliative Care Interventions in Advanced Dementia

    Jeanmarie B. Rey, Jeffrey R. Bevan, Jill E. Danyluk

    Advance care planning interventions for people with advanced dementia likely increase the documentation of advance directives and the number of discussions about goals of care with family decision-makers.

    U.S. Preventive Services Task Force

    Screening for Chlamydia and Gonorrhea

    Review the most recent recommendations from the USPSTF.

    Putting Prevention Into Practice

    Screening for Chlamydia and Gonorrhea

    Brandy Peaker, Emilie Biondokin

    This PPIP quiz is based on the recommendations of the USPSTF.

    Photo Quiz

    Descending Maculopapular Rash in a Child

    Sungyub Lew, Jacqueline Lau, Nada Al-Hashimi

    A 10-year-old girl presented with headache, cough, and morbilliform rash.

    Circular Skin Lesion

    Jeremy D. Schroeder, Marco Jose Dela Cruz

    A patient presented with mildly tender, circular, hyperpigmented skin lesions with small bumps affecting the dorsum of both hands and the medial aspect of one foot.

    FPIN's Clinical Inquiries

    Does Exercise During Pregnancy Decrease the Risk of Developing Hypertensive Disorders?

    Richard Wolferz, Misha Fotoohi, Saskia Spiess, Dominik Ose, Brian Vukelic, Katherine T. Fortenberry

    Exercise regimens initiated early in pregnancy and performed consistently are an effective way to reduce a patient’s risk of developing gestational hypertension and preeclampsia.

    FPIN's Help Desk Answers

    Effectiveness of Epidural Steroid Injections for Low Back Pain

    Socorro Shelton, Andrew Yochum, Ethan Walker, Nicole Waters

    Treatment with epidural steroid injections in the lower spine is not effective for reducing pain and disability.


    Abametapir 0.74% (Xeglyze) for the Treatment of Head Lice

    Meera Sunder

    Abametapir is shown to be an effective treatment for head lice infestation in patients six months and older.

    Diagnostic Tests

    Coronary Artery Calcium Scoring for Prevention of Cardiovascular Disease

    Hiu Ying Joanna Choi

    A CAC score is a strong predictor of CHD, CVD, and mortality risk and provides risk discrimination and stratification beyond that provided by traditional risk factor models.

    Curbside Consultation

    Assisting Adult Protective Services in Addressing Maltreatment in Older Adults

    Brian K. Unwin, Sarah L. Stubbs, Holly D’Heron

    Elder abuse affects at least one in 10 older adults but is often undetected and underreported, even compared with any other form of abuse.


    Closed-Loop System Improves Glycemic Control but Not Hypoglycemia for Young Children With Type 1 Diabetes Mellitus

    Mark H. Ebell

    Several Drugs Are Effective for Weight Loss in Obese or Overweight Adults; It Is Unclear Whether They Improve Health Outcomes

    Henry C. Barry

    All-Cause Mortality Is Comparable in Patients With Left Main Coronary Artery Disease Treated With PCI or CABG

    Henry C. Barry

    Proton Pump Inhibitor Use Associated With an Increased Risk of Gastric Cancer

    Mark H. Ebell

    Practice Guidelines

    High-Flow Nasal Oxygen for Acute Respiratory Failure: Guidelines From the American College of Physicians

    C.R. Rohrbough, Matthew Pflipsen

    The American College of Physicians published guidelines for use of HFNO in adults based on a systematic review focusing on all-cause mortality, hospital length of stay, hospital-acquired pneumonia, intubation/reintubation, intensive care unit admissions, and patient comfort.

    Palliative Care of Patients With Cancer: Guidelines From the National Comprehensive Cancer Network

    Michael J. Arnold

    The National Comprehensive Cancer Network has updated recommendations for palliative care of patients with cancer.

    Letters to the Editor

    Case Report: Multiple Supernumerary Nipples in a Young Woman

    Allison Kirchner, Priyanka Patel, Sheryl Hoyer

    Treatment of Chagas Disease in Breastfeeding Dyads

    Cherec Morrison, Nithya Natrajan, Lindsay Snow

    Reply: Paul T. Cantey, Susan P. Montgomery, Anne Straily

    Information from Your Family Doctor

    Celiac Disease

    Celiac (SEE-lee-ack) disease is swelling in the stomach caused by eating gluten. Gluten is a protein in foods made with grains such as wheat, rye, or barley. The swelling stops your body from getting the nutrients it needs. It can occur at any age. About one in 100 people...

    RED-S in the Active Female

    Relative energy deficiency in sport (RED-S) affects active people. It happens when they burn more calories than they take in. It used to be called the female athlete triad. RED-S affects males and females differently. Not having enough available energy affects the way our...


    All editors in a position to control content for this activity, AFP journal, are required to disclose any relevant financial relationships. View disclosures.

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