• Articles

    Chronic Asthma Treatment: Common Questions and Answers

    Tyler J. Raymond, Thomas A. Peterson, Jessica Coulter

    This article reviews common questions about outpatient asthma treatment and provides evidence-based answers.

    Outpatient Management of COVID-19: Rapid Evidence Review

    Anthony M. Cheng, Emily Dollar, Heather Angier

    This article summarizes the prevention, diagnosis, and treatment of COVID-19, with a particular emphasis on outpatient management. Characteristics of the predominant variants of concern should determine aspects of diagnosis and treatment.

    Systemic Lupus Erythematosus: Diagnosis and Treatment

    Nguyet-Cam V. Lam, Judy Abu Brown, Richa Sharma

    Systemic lupus erythematosus should be considered in patients with symptoms involving multiple organ systems after infectious causes have been ruled out. Management is directed at complete remission or low disease activity, minimizing the use of glucocorticoids, preventing...

    Leukemia: What Primary Care Physicians Need to Know

    Joanne T. C. Gbenjo, Georgia L. M. McCrary, Sarah E. Wilson

    This article reviews common presentations of leukemia subtypes, initial diagnostic evaluation, principles of therapy, and long-term sequelae in leukemia survivors.

    Top 20 Research Studies of 2022 for Primary Care Physicians

    Roland Grad, Mark H. Ebell

    The annual installment of this series summarizes the top studies of 2022, which were summarized as POEMs (patient-oriented evidence that matters). Topics in this group of studies include preventive health care, behavioral health, asthma, gastroenterology, and diabetes.

    Bell Palsy: Rapid Evidence Review

    Sarah N. Dalrymple, Jessica H. Row, John Gazewood

    Bell palsy is the acute onset of unilateral facial weakness or paralysis. Treatment includes oral corticosteroids with or without oral antivirals. The overall prognosis is good, and most patients recover completely within three weeks.


    Recent Changes in International Asthma Guidelines May Be Influenced by Pharmaceutical Industry Conflicts of Interest

    Steven R. Brown

    Asthma treatment recommendations have recently changed. These recommendations and the randomized controlled trials of SMART were heavily influenced by the pharmaceutical industry.

    Legal Challenges for Family Physicians in the Post–Roe v Wade Era

    Emily Kirchner

    The Supreme Court's Dobbs ruling has created confusion about legal rights to abortion care and legal risks for providing or supporting reproductive health care.

    AFP Clinical Answers

    Cardiovascular Disease, Fracture Healing, Anxiety in Children, Antibiotic Duration, Cervical Spine Injuries

    Key clinical questions and their evidence-based answers directly from the journal’s content, written by and for family physicians.

    Medicine by the Numbers

    Electronic Cigarettes for Smoking Cessation

    Kento Sonoda, Kaku Kuroda

    Because no data from a long-term safety profile are available, we have assigned a color recommendation of yellow (unclear benefits) to this review, despite the promising certainty of evidence supporting nicotine e-cigarettes for smoking cessation.

    Cochrane for Clinicians

    Magnetic Resonance Imaging for Diagnosing Acute Appendicitis

    Anne Mounsey, Brock Cardon

    In pregnant patients, children, and adults with clinical signs and symptoms of appendicitis, MRI has an overall sensitivity of 95% and specificity of 96%. The posttest probability of having appendicitis after a positive MRI is 90% and 2% after a negative MRI, assuming a...

    Accuracy of Point-of-Care Rapid Antigen Tests for Diagnosis of COVID-19

    Karl T. Clebak, Jessica Snyder, Todd M. Felix

    SARS-CoV-2 antigen tests have an average sensitivity of 69.3% and specificity of 99.3%. Accuracy depends on the presence or absence of symptoms, time from symptom onset, and test brand.

    Graham Center Policy One-Pager

    Relationships Matter: Primary Care Physicians and Usual Sources of Care

    Alison N. Huffstetler, Anuradha Jetty, Ann Greiner, Yalda Jabbarpour

    There are benefits to having a primary care physician or a usual source of care. Yet, the overall percentage of U.S. patients who reported having a usual source of care declined from 84% in 2000 to 74% in 2019, with wide variations across states, patient race, and insurance...

    U.S. Preventive Services Task Force

    Screening for Hearing Loss in Older Adults: Clinical Summary of the USPSTF Recommendation

    The U.S. Preventive Services Task Force concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for hearing loss in older adults.

    FPIN's Clinical Inquiries

    Metformin vs. Lifestyle Changes for Prevention of Type 2 Diabetes Mellitus

    Elin Kondrad, Allyson Westling, Erika Burke, Stephanie Weldon

    Metformin is more effective than standard lifestyle changes at preventing progression to type 2 diabetes. However, intensive lifestyle interventions are as effective as metformin. The effects of these interventions are enduring, with a continued benefit of intensive lifestyle...

    FPIN's Help Desk Answers

    Does the Consumption of Red and Processed Meats Increase the Risk of Cancer?

    Linsey Christensen, Matias Calquin, Sarah Daly

    Patients should consume less red and processed meat. Higher meat consumption increases the risk of breast, colorectal, colon, rectal, and lung cancers.

    Photo Quiz

    Rapidly Growing Skin Lesion

    Megan Cranor, Megha Gangadhar, Suchitra Nair

    A patient presented with a sharply-demarcated, firm, erythematous lesion on her right medial thigh that was nonfluctuant and had a punctate central plug.

    Ankle Pain and Rash

    Keifer Walsh, Alexis Bowen, Moses Cheng

    A patient presented with multiple skin lesions and a painful swollen right ankle.

    Diary of a Family Physician

    Diary of a Family Physician

    Annette Chavez

    First-person accounts from the front lines of family medicine.


    Improved Decongestion With the Addition of Acetazolamide to Intravenous Loop Diuretics for Acute Heart Failure

    Nita Shrikant Kulkarni

    Rebound Symptoms Common With COVID-19 Even After Placebo Treatment

    Mark H. Ebell

    Invitation to a Single Colonoscopy Has Only Modest Impact on Colorectal Cancer Incidence

    Mark H. Ebell

    Liraglutide Is Probably the Best Second Drug to Prevent Cardiovascular Events in Patients With Type 2 Diabetes Mellitus Who Take Metformin

    Mark H. Ebell

    Practice Guidelines

    Management of Low Back Pain: Guidelines From the VA/DoD

    Andrew Buelt, Sara McCall, Jill Coster

    The U.S. Department of Veterans Affairs and U.S. Department of Defense (VA/DoD) have published guidelines on the diagnosis and treatment of low back pain.

    Management of Postpartum Hemorrhage: Recommendations From FIGO

    Daniel S. Hwang, Leslie Myers

    The International Federation of Gynecology and Obstetrics (FIGO) published new guidelines for the prevention and management of postpartum hemorrhage.

    Letters to the Editor

    Intravenous Iron Replacement for Iron Deficiency Anemia [FPIN's Clinical Inquiries]

    Barry Cooper

    Commercial Oats and Patients With Celiac Disease

    Alan M. Ehrlich

    Information from Your Family Doctor

    Lupus: What You Should Know

    Lupus is a disease of the immune system. It can affect many parts of the body. Normally, the immune system makes antibodies to protect the body against infections. In people who have lupus, the immune system becomes overactive and attacks healthy cells and tissues by mistake.

    Leukemia: The Basics

    Leukemia (loo-KEE-me-uh) is cancer of the blood and bone marrow. People of any age can get it. The cause is often not clear. You may be at higher risk if you were exposed to radiation or certain chemicals and pesticides, or if you have certain genetic disorders. If you have...

    Bell Palsy

    Bell palsy is paralysis of the muscles on one side of the face (see drawing). It usually develops over one to three days, and then slowly improves or completely goes away in one to three months. Most people with Bell palsy recover completely, but some are left with weakness...


    All editors in a position to control content for this activity, AFP journal, are required to disclose any relevant financial relationships. View disclosures.

    Tag Legend


    CME Continuing Medical Education Credit
    POC Point-of-Care Resource
    FREE Free Access
    Alg Algorithm
    DDx Differential Diagnosis
    PtEd Patient Education