• Articles

    Gallstone Disease: Common Questions and Answers

    Hiten Patel, Jacqueline Jepsen

    Gallstones affect an estimated 10% to 15% of U.S. adults. Nearly 80% of gallstones are found incidentally and remain asymptomatic. Risk factors vary; they include chronic disease, lifestyle choices, medications, and demographics.

    Management of Spontaneous Vaginal Delivery

    Kathryn A. McKenna, Laura Leaman

    Spontaneous vaginal delivery is inherently associated with risks to the mother and fetus that can lead to morbidity. Knowledge of these risks and management of each stage of labor can help minimize potential harms.

    Rosacea: Common Questions and Answers

    Winfred Frazier, Raquel K. Zemtsov, Yufei Ge

    The diagnosis of rosacea is made based on the updated 2017 National Rosacea Society Expert Committee guidelines, including fixed erythema, phymatous changes of skin thickening due to sebaceous gland hyperplasia and fibrosis, papules, pustules, telangiectasia, and flushing....

    Testosterone Replacement Therapy for Male Hypogonadism

    Joel J. Heidelbaugh, Aleksandr Belakovskiy

    After discussing the potential benefits and risks of testosterone replacement therapy through shared decision-making, it should be considered for men with testosterone deficiency to correct selected symptoms and induce and maintain secondary sex characteristics.

    Salivary Gland Disorders: Rapid Evidence Review

    Michael J. Kim, Anna Milliren, Dennis J. Gerold, Jr.

    Inflammation of the salivary glands is caused by bacterial, viral, and obstructive etiologies. Most disorders are managed with conservative measures by treating the underlying cause, optimizing predisposing factors, controlling pain, and increasing salivary flow.

    Lifelong Care of Patients After Gender-Affirming Surgery

    Quinn Jackson, Nicole T. Yedlinsky, Meredith Gray

    This article provides an overview of gender-affirming surgery with a focus on anatomic changes, how to perform routine physical examinations, and how gender-affirming surgery may alter a patient's care throughout their life.


    Prioritizing the 5Ms in Geriatric Care: A Holistic Approach to Care of the Older Adult

    Namirah Jamshed, Anupama Gangavati

    The 5Ms framework offers a comprehensive approach to the care of older adults and emphasizes patient-centered strategies and interdisciplinary coordination. It has been shown to improve outcomes, reduce low-quality services, and increase the use of cost-effective services.

    Chatbots and Large Language Models in Family Medicine

    Aaron Saguil

    Health care practices are increasingly turning to Large Language Models, the backbone of chatbots, to help decrease administrative burden and combat burnout.

    AFP Clinical Answers

    Gestational Diabetes Mellitus, Acetaminophen Overdose, Congenital Syphilis, e-Cigarettes, Acne Vulgaris, Newborn Birthmarks

    Key clinical questions and their evidence-based answers directly from the journal’s content, written by and for family physicians.

    Medicine by the Numbers

    Combined Oral Contraceptive Pills for Primary Dysmenorrhea

    Stephanie Algenio-Anciro, Christina Valerio

    Given the reported potential benefits, relatively low rate of adverse events, and the noted limitations along with the potential for bias in the findings, we have assigned a color recommendation of yellow (unclear benefits/ more data needed) to the use of combined OCPs for...

    Cochrane for Clinicians

    Combined Oral Contraceptives for Primary Dysmenorrhea

    Dustin K. Smith, Bristal Thompson, Samantha Keefer, Helen Haskell

    In early postmenopausal women, systemic estrogen slightly improves sexual function (i.e., desire, arousal, lubrication, orgasm, satisfaction, and pain). However, it is not clear whether other types of hormone therapy improve sexual function in postmenopausal women.

    Hormone Therapy for Sexual Function in Postmenopausal Women

    Donna Cohen, Emily Brown

    Does hormone therapy improve sexual function in post-menopausal women?

    U.S. Preventive Services Task Force

    Primary Care Interventions to Prevent Child Maltreatment

    The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of primary care interventions to prevent child maltreatment.

    Diary of a Family Physician

    Diary of a Family Physician

    Annette Chavez

    First-person accounts from the front lines of family medicine.

    Photo Quiz

    A Growing Goiter

    Courtney Humphrey, Riley C. McHugh

    A 27-year-old woman presented with a mass on the front of her neck.

    White Worms

    Jesse Schönau

    A 9-year-old girl presented with acute painful irritation in her genital and anal area.

    Point-of-Care Guides

    Carpal Tunnel Syndrome

    Christopher A. Alvarez, Steven R. Brown

    How is carpal tunnel syndrome diagnosed clinically, and how can the history and physical examination inform evidence-based management?

    FPIN's Clinical Inquiries

    Bempedoic Acid for the Prevention of Cardiovascular Disease

    Anne Mounsey, Maniraj Jeyaraju

    Bempedoic acid can be used to effectively treat hyperlipidemia. Bempedoic acid decreases the incidence of major adverse cardiovascular events, with insignificant increases in liver enzyme and creatine kinase levels, gout, myalgia, and cholelithiasis.

    Lown Right Care

    Avoiding Racist and Judgmental Clinical Documentation: Helping to Achieve Health Equity

    Alan R. Roth, Andy Lazris, Helen Haskell, John James

    A collaboration between AFP and the Lown Institute promotes a vision of delivering health care that is based on evidence, balanced in its approach, and focused on the patient.


    RSVpreF (Abrysvo) and Nirsevimab-alip (Beyfortus) for the Prevention of Respiratory Syncytial Virus Infection

    Matthew Nodelman, A. Miles Scott

    RSVpreF and nirsevimab-alip are effective for the prevention of RSV-associated LRTI, severe LRTI, and hospitalizations in infants entering their first RSV season.


    Consider a Formal Exercise Prescription as Initial Therapy for Patients With Symptoms of Depression

    Allen F. Shaughnessy

    Oseltamivir Does Not Reduce the Likelihood of Hospitalization in Adults

    Mark H. Ebell

    Canadian Thoracic Society Guidelines for Pharmacotherapy for Stable Chronic Obstructive Pulmonary Disease

    Mark H. Ebell

    Baseline Urate Level in Adults With History of Acute Gout Is Associated With the Risk of Subsequent Gout Flare-ups

    David C. Slawson

    Practice Guidelines

    Lipid Management: Guidelines From the Canadian PEER Group for Primary Care

    Laura Blinkhorn, Andrew Buelt

    The Canadian PEER group for primary care released guidelines for preventing and managing CVD through lipid management.

    Management of Bipolar Disorder: Guidelines From the VA/DoD

    Michael J. Arnold

    The U.S. Department of Veterans Affairs and U.S. Department of Defense (VA/DoD) published new recommendations for diagnosing and managing bipolar disorder.

    Letters to the Editor

    Addressing Mood Disorders in Infertility Care

    Megan Killeen



    Incorrect Quiz Answers. In the April 2024 issue, the “Answers to This Issue's CME Quiz” answer box listed incorrect answers for questions 12 and 14. The correct answer choice for both should have been B. The online version of the CME Quiz for this issue was not affected.


    All editors in a position to control content for this activity, AFP journal, are required to disclose any relevant financial relationships. View disclosures.

    Tag Legend


    CME Continuing Medical Education Credit
    POC Point-of-Care Resource
    FREE Free Access
    Alg Algorithm
    DDx Differential Diagnosis
    PtEd Patient Education