August 1, 2019

Tendons have a complex biology that provides strength, flexibility, and elasticity but also predisposes them to injury. Insidious onset of pain and dysfunction is a common presentation for most tendinopathies. Diagnosis is typically based on history and physical examination…

Ingrown toenails most commonly affect the great toe; they account for 20% of foot problems in primary care. They most commonly occur in young men, and nail care habits and footwear are common contributing factors. Ingrown nails can be treated nonsurgically (for mild to moderate…

Hirsutism is the excessive growth of terminal hair in a typical male pattern in a female. It is often a sign of excessive androgen levels. Polycystic ovary syndrome and idiopathic hyperandrogenism account for most cases. Women with an abnormal hirsutism score should be…

Yes: High-Quality Evidence Supports Metformin Use in Persons at High Risk

No: Evidence Does Not Show Improvements in Patient-Oriented Outcomes

Is adding a long-acting beta-agonist to an inhaled corticosteroid safe for patients with persistent asthma? | Should asymptomatic adults be screened for PAD and cardiovascular disease with the ankle-brachial index? | What infectious disease screenings and vaccinations are…

Influenza vaccination reduces rates of laboratory-confirmed influenza and symptomatic influenza-like illness in healthy children, healthy adults, and older adults. There is no consistent evidence that influenza vaccination reduces school absenteeism in children, parental…

A healthy 21-year-old male soldier stationed in Qatar presented with abdominal cramping that began two weeks prior. The pain, which he rated as a 7 out of 10, was brought on by eating. Although this resulted in him eating less to avoid the pain, he did not have significant…

Which noninvasive nonpharmacologic treatments for chronic neck pain improve function or pain for at least one month?

The only cardiovascular benefit to treatment with dapagliflozin was a reduction in the likelihood of hospitalization; 125 patients would need to be treated for 10 years to prevent one hospitalization.

Antibiotics do not benefit patients hospitalized with an asthma exacerbation. Evidence from this study suggests worse outcomes with antibiotic use, including a longer hospital stay, higher costs, and greater risk of diarrhea.

Infantile hemangiomas are the most common benign tumors of childhood, occurring in up to approximately 5% of infants. These benign vascular tumors are small, self-resolving, and do not require treatment.

This meta-analysis provides high-quality evidence that ?exible sigmoidoscopy and fecal occult blood testing both reduce the risk of death from colorectal cancer. The study did not provide a clear answer regarding a superior screening modality, so the decision to choose one test…

Skin-to-skin-contact in the immediate postnatal period should be recommended to all mothers because it is associated with a higher likelihood of exclusive breastfeeding at hospital discharge and for up to six months afterward (number needed to treat [NNT] = 5 to 8).

An ingrown toenail occurs when the side or corner of the nail digs into the skin of the toe. This happens mostly to the big toenail, but it can happen to any toenail.