September 15, 2020

Articles

Basal Cell and Cutaneous Squamous Cell Carcinomas: Diagnosis and Treatment

Jonathon M. Firnhaber

Keratinocyte carcinoma is the most common skin cancer malignancy found in humans. It is comprised of basal cell carcinoma and cutaneous squamous cell carcinoma. Basal cell carcinomas can develop early in life, sporadically, and with certain genetic syndromes. Age is an…

Management of Hypertriglyceridemia: Common Questions and Answers

Robert C. Oh, Evan T. Trivette, Katie L. Westerfield

Hypertriglyceridemia is associated with increased risk of cardiovascular disease, and severely elevated triglyceride levels increase the risk of pancreatitis. Common risk factors include obesity, metabolic syndrome, and type 2 diabetes mellitus. Management starts with lifestyle…

Anaphylaxis: Recognition and Management

Matthew C. Pflipsen, Karla M. Vega Colon

Common symptoms of anaphylaxis are urticaria, difficulty breathing, and mucosal swelling, and most anaphylactic reactions occur outside the hospital setting. Acute management of anaphylaxis involves removal of the trigger; early administration of intramuscular epinephrine…

Editorials

Keratinocyte Carcinomas: Should We Screen for Them?

Michael P. Pignone, Adewole S. Adamson

Keratinocyte carcinoma, which includes basal cell and cutaneous squamous cell carcinomas, is common, and the incidence is increasing. According to the Centers for Medicare and Medicaid Services, the estimated number of keratinocyte carcinomas diagnosed in the United States in…

AFP Clinical Answers

VTE, Antiplatelet Therapy, Treatment for Veterans, HIV Prophylaxis, Diabetes Mellitus Screening

Key clinical questions and their evidence-based answers directly from the journal’s content, written by and for family physicians.

Lown Right Care

Appropriate Use of Opioids for Chronic Pain

Alan R. Roth, Andy Lazris, Helen Haskell, John James

A collaboration between AFP and the Lown Institute promotes a vision of delivering health care that is based on the evidence, balanced in its approach, and focused on the patient.

U.S. Preventive Services Task Force

Screening for Hepatitis C Virus Infection in Adolescents and Adults: Recommendation Statement

The USPSTF recommends screening for hepatitis C virus infection in adults aged 18 to 79 years.

Putting Prevention Into Practice

Screening for Hepatitis C Virus Infection in Adolescents and Adults

Iris Mabry-Hernandez, Karen Li

M.S. is a 20-year-old man who presents for a preemployment physical examination. He states that he is single, has two or three drinks per month on social occasions, does not smoke, is sexually active, and does not use illicit drugs.

Photo Quiz

Persistent Asymptomatic Rash

Kyle P. Lammlein, Jillian E. Sylvester

A soldier deployed to Afghanistan presented with an asymptomatic ulcerated lesion on the arm.

Point-of-Care Guides

Diverticulitis: Predicting Which Patients with Acute Abdominal Pain Have the Disease

Aaron Saguil

Is it possible to determine which patients with acute abdominal pain are likely to have diverticulitis and therefore do not require imaging?

STEPS

Lefamulin (Xenleta) for the Treatment of Community-Acquired Bacterial Pneumonia

Todd M. Felix, Kelly Karpa

Lefamulin may be considered for patients hospitalized with community-acquired bacterial pneumonia.

POEMs

Denosumab No Better than Bisphosphonates for Preventing Fracture, and the Cost Is Much Higher

Mark H. Ebell

This meta-analysis found no evidence that the monoclonal antibody denosumab reduces the risk of fracture more than bisphosphonates.

ACR Guideline for Managing Patients with Degenerative Joint Disease of the Hand, Knee, and Hip

Henry C. Barry

This meta-analysis found no evidence that the monoclonal antibody denosumab reduces the risk of fracture more than bisphosphonates.

Fecal Microbiota Transplant Effective for Irritable Bowel Syndrome

Mark H. Ebell

This is the largest and best study to date of fecal microbiota transplant for irritable bowel syndrome —with impressive results.

Practice Guidelines

Chronic Kidney Disease: Evaluation and Treatment Guidelines from the VA/DoD

Michael J. Arnold, Andrew Buelt

The U.S. Department of Veterans Affairs and Department of Defense have updated recommendations for evaluation and treatment of chronic kidney disease.

Letters to the Editor

CME Course Information

Evidence-based Medicine Toolkit

Strength of Recommendation Taxonomy

Advertising: Career Opportunities (PDF download)

Disclosures

All editors in a position to control content for this activity, AFP journal, are required to disclose any relevant financial relationships. View disclosures.

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