Articles
Basal Cell and Cutaneous Squamous Cell Carcinomas: Diagnosis and Treatment
Keratinocyte carcinoma is the most common skin cancer malignancy found in humans. It is comprised of basal cell carcinoma and cutaneous squamous cell carcinoma. Basal cell carcinomas can develop early in life, sporadically, and with certain genetic syndromes. Age is an…
Management of Hypertriglyceridemia: Common Questions and Answers
Hypertriglyceridemia is associated with increased risk of cardiovascular disease, and severely elevated triglyceride levels increase the risk of pancreatitis. Common risk factors include obesity, metabolic syndrome, and type 2 diabetes mellitus. Management starts with lifestyle…
Anaphylaxis: Recognition and Management
Common symptoms of anaphylaxis are urticaria, difficulty breathing, and mucosal swelling, and most anaphylactic reactions occur outside the hospital setting. Acute management of anaphylaxis involves removal of the trigger; early administration of intramuscular epinephrine…
Editorials
Keratinocyte Carcinomas: Should We Screen for Them?
Keratinocyte carcinoma, which includes basal cell and cutaneous squamous cell carcinomas, is common, and the incidence is increasing. According to the Centers for Medicare and Medicaid Services, the estimated number of keratinocyte carcinomas diagnosed in the United States in…
AFP Clinical Answers
VTE, Antiplatelet Therapy, Treatment for Veterans, HIV Prophylaxis, Diabetes Mellitus Screening
Key clinical questions and their evidence-based answers directly from the journal’s content, written by and for family physicians.
Lown Right Care
Appropriate Use of Opioids for Chronic Pain
A collaboration between AFP and the Lown Institute promotes a vision of delivering health care that is based on the evidence, balanced in its approach, and focused on the patient.
U.S. Preventive Services Task Force
Screening for Hepatitis C Virus Infection in Adolescents and Adults: Recommendation Statement
The USPSTF recommends screening for hepatitis C virus infection in adults aged 18 to 79 years.
Putting Prevention Into Practice
Screening for Hepatitis C Virus Infection in Adolescents and Adults
M.S. is a 20-year-old man who presents for a preemployment physical examination. He states that he is single, has two or three drinks per month on social occasions, does not smoke, is sexually active, and does not use illicit drugs.
Photo Quiz
Persistent Asymptomatic Rash
A soldier deployed to Afghanistan presented with an asymptomatic ulcerated lesion on the arm.
Point-of-Care Guides
Diverticulitis: Predicting Which Patients with Acute Abdominal Pain Have the Disease
Is it possible to determine which patients with acute abdominal pain are likely to have diverticulitis and therefore do not require imaging?
STEPS
Lefamulin (Xenleta) for the Treatment of Community-Acquired Bacterial Pneumonia
Lefamulin may be considered for patients hospitalized with community-acquired bacterial pneumonia.
POEMs
Denosumab No Better than Bisphosphonates for Preventing Fracture, and the Cost Is Much Higher
This meta-analysis found no evidence that the monoclonal antibody denosumab reduces the risk of fracture more than bisphosphonates.
ACR Guideline for Managing Patients with Degenerative Joint Disease of the Hand, Knee, and Hip
This meta-analysis found no evidence that the monoclonal antibody denosumab reduces the risk of fracture more than bisphosphonates.
Fecal Microbiota Transplant Effective for Irritable Bowel Syndrome
This is the largest and best study to date of fecal microbiota transplant for irritable bowel syndrome —with impressive results.
Practice Guidelines
Chronic Kidney Disease: Evaluation and Treatment Guidelines from the VA/DoD
The U.S. Department of Veterans Affairs and Department of Defense have updated recommendations for evaluation and treatment of chronic kidney disease.
Letters to the Editor
Case Report: Multisystem Inflammatory Syndrome in a Child Presenting with Rash and Fever
Letter
Case Report: Multiple Myiasis from Dermatobia hominis After Travel to Costa Rica
Letter
Case Report: Handwashing-Induced Dermatitis During the COVID-19 Pandemic
Letter
