Articles
Peripheral Nerve Entrapment and Injury in the Upper Extremity
Peripheral nerves in the upper extremities are at risk of injury and entrapment because of their superficial nature and length. Injury can result from trauma, anatomic abnormalities, systemic disease, and entrapment. Most peripheral nerve injuries seen by family physicians will…
Difficult-to-Treat and Severe Asthma: Management Strategies
In difficult-to-treat asthma, the disease is uncontrolled despite adherence to inhaled corticosteroid therapy in combination with a second controller, an oral corticosteroid is needed to achieve control, or it is uncontrolled despite oral corticosteroid therapy. Severe asthma…
Initiating Hormonal Contraception
Most patients can safely begin using hormonal contraception at any point during their menstrual cycle. A flexible, patient-centered approach to initiating contraception promotes health and enhances patients' reproductive autonomy. A recent Papanicolaou test is not necessary…
Editorials
Enhancing Diabetes Self-Management Education and Support in Clinical Practice
Health systems and family physicians should mobilize to ensure that all people with type 2 diabetes have access to diabetes self-management education and support, including nutritional, physical, and emotional support.
AFP Clinical Answers
Antidepressants for Older People, Point-of-Care Ultrasonography, BRCA Testing, Probiotics
What are the adverse events of antidepressants in adults 65 years and older with major depressive disorder? | What urgent medical conditions can be diagnosed by point-of-care ultrasonography? | Which women are recommended for breast cancer susceptibility 1 and 2 (<i>BRCA 1/2</i…
Cochrane for Clinicians
Alcoholics Anonymous and Other 12-Step Facilitation Programs for Alcohol Use Disorder
Manualized (standardized and replicable) Alcoholics Anonymous and similar 12-step facilitation programs produce higher rates of continuous abstinence than other established treatments.
Structural MRI for the Early Diagnosis of Alzheimer Disease in Patients with MCI
There is insufficient evidence to recommend structural brain magnetic resonance imaging to diagnose Alzheimer disease in patients with mild cognitive impairment.
Curbside Consultation
Caring for the Physician Affected by Substance Use Disorder
A 34-year-old physician, H.M., is an established patient in my practice. H.M. presents for a follow-up visit after finishing inpatient treatment for opioid use disorder.
Photo Quiz
Erosions and Vesicles in a Febrile Infant
A five-month-old child with a history of dry skin presented with a spreading rash and fever.
FPIN's Clinical Inquiries
Platelet-Rich Plasma vs. Corticosteroids for Refractory Plantar Fasciitis
Platelet-rich plasma injections are similar to corticosteroids for pain relief and improvement in function in patients with refractory plantar fasciitis lasting less than 12 weeks.
Diagnostic Tests
Serum Lactate Testing to Predict Mortality in Patients with Sepsis
Management of patients with sepsis is challenging and mortality is high. Early diagnosis and prompt initiation of therapy are essential. Higher lactate levels correlate with increased risk of mortality, particularly with lactate levels greater than 4.0 mmol per L and in the…
POEMs
Bone Mineral Density Testing: One and Done
Rechecking bone mineral density (BMD) after three years does not add additional prognostic information. Serial BMD testing is not useful in estimating fracture risk and assessing the need for treatment because BMD does not change much within three years.
Better Primary Care Continuity Is Associated with Lower Mortality Risk
Most studies in this systematic review found a protective effect of greater primary care continuity and all-cause mortality.
HPV Vaccine, Especially Before Age 17, Is Associated with a Large Reduction in Invasive Cervical Cancer
HPV vaccination is associated with a significant reduction in the likelihood of invasive cervical cancer.
Low-Dose Edoxaban Effective for Stroke Prevention in Older Patients with Atrial Fibrillation
A lower dose of edoxaban is effective in decreasing stroke and systemic embolism in older patients with atrial fibrillation compared with placebo.
Practice Guidelines
Colonoscopy Follow-up: U.S. Multi-Society Task Force on Colorectal Cancer Updates Recommendations
Screening colonoscopy findings define the future risk of colorectal cancer and the need for repeat screening. The U.S. Multi-Society Task Force on Colorectal Cancer updated recommended follow-up intervals after screening colonoscopy in average-risk individuals.
Medicine by the Numbers
Antiplatelet Agents for Preventing Early Recurrence of Ischemic Stroke or TIA
After atherothrombotic ischemic stroke or transient ischemic attack, adding clopidogrel to aspirin reduced recurrent strokes but increased major hemorrhages.
Letters to the Editor
Corrections
Corrections
Incorrect Figure Legends. In the article, “Hip Pain in Adults: Evaluation and Differential Diagnosis,” (January 15, 2021, p. 81), the legend for Figure 3B incorrectly listed abducts instead of adducts. It should have read: “Flexion adduction internal rotation test. The examiner…
Corrections
Incorrect Unit of Measure. In the article, “Eating Disorders in Primary Care: Diagnosis and Management,” (January 1, 2021, p. 22), the second sentence of the Nutrition section (page 25) incorrectly added “per kg” to the number of daily required kcal for adolescent females and…
Corrections
Incorrect statistics. In the article, “Breast Cancer Screening: Common Questions and Answers,” (January 1, 2021, p. 33), the figure listed for breast cancer deaths per number of women screened with mammography should have been per 10,000 women rather than per 100,000 women in…
