STEPS
New Drug Reviews

RSVpreF (Abrysvo) and Nirsevimab-alip (Beyfortus) for the Prevention of Respiratory Syncytial Virus Infection

Matthew Nodelman, MD,
A. Miles Scott, DO,
Prisma Health/University of South Carolina School of Medicine–Columbia, Columbia, South Carolina

American Family Physician. 2024;109(6):578-579.

Author disclosure: No relevant financial relationships.

Address correspondence to Matthew Nodelman, MD, at matthew.nodelman@prismahealth.org. Reprints are not available from the authors.

Author disclosure: No relevant financial relationships.

  1. 1.DailyMed. Drug label information. Abrysvo—respiratory syncytial virus vaccine kit. Accessed January 10, 2024. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=be18292e-b1a2-4815-a0ed-003efaa6bea3#leftmenu
  2. 2.DailyMed. Drug label information. Beyfortus—nirsevimab injection. Accessed January 10, 2024. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2f08fa60-f674-432d-801b-1f9514bd9b39#ID_f92d84a4-7a21-4a02-acf9-9d01dda07f0a
  3. 3.Drysdale SB, Cathie K, Flamein F, et al.; HARMONIE Study Group. Nirsevimab for prevention of hospitalizations due to RSV in infants. N Engl J Med. 2023;389(26):2425-2435.
  4. 4.Hammitt LL, Dagan R, Yuan Y, et al.; MELODY Study Group. Nirsevimab for prevention of RSV in healthy late-preterm and term infants. N Engl J Med. 2022;386(9):837-846.
  5. 5.Kampmann B, Madhi SA, Munjal I, et al.; MATISSE Study Group. Bivalent prefusion F vaccine in pregnancy to prevent RSV illness in infants. N Engl J Med. 2023;388(16):1451-1464.
  6. 6.American Academy of Pediatrics. Patient care. Nirsevimab (Beyfortus) product & ordering information. Updated October 11, 2023. Accessed January 10, 2024. https://www.aap.org/en/patient-care/respiratory-syncytial-virus-rsv-prevention/nirsevimab-beyfortus-product--ordering-information/

STEPS new drug reviews cover Safety, Tolerability, Effectiveness, Price, and Simplicity. Each independent review is provided by authors who have no financial association with the drug manufacturer.

This series is coordinated by Allen F. Shaughnessy, PharmD, assistant medical editor.

A collection of STEPS published in AFP is available at https://www.aafp.org/afp/steps.

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