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FPIN's Clinical Inquiries
From the Family Practice Inquiries Network

Ultrasound- vs Landmark-Guided Steroid Injection for Carpal Tunnel Syndrome

Hendrik Stegall, MD
Scott Hall, MD
Laura Elizabeth Moreno, MD

American Family Physician. 2025;111(2):173-174.

Author disclosure: No relevant financial relationships.

HENDRIK STEGALL, MD; SCOTT HALL, MD; and LAURA ELIZABETH MORENO, MD; University of Utah Health, Salt Lake City.

Address correspondence to Hendrik Stegall, MD, at hendrik.stegall@hsc.utah.edu.

Author disclosure: No relevant financial relationships.

  1. 1.Ashworth NL, Bland JDP, Chapman KM, et al. Local corticosteroid injection versus placebo for carpal tunnel syndrome. Cochrane Database Syst Rev. 2023(2):CD015148.
  2. 2.Jiang A, Qian Y, Yan J, et al. Corticosteroid injection for carpal tunnel syndrome: a meta-analysis comparing ultrasound guided approach with landmark approach. Pak J Med Sci. 2024;40(4):773-778.
  3. 3.Alhindi AK, Ghaddaf AA, Alomari MS, et al. Effect of ultrasound-guided versus landmark-guided local corticosteroid injection for carpal tunnel syndrome: a systematic review and meta-analysis. Arch Orthop Trauma Surg. 2023;143(1):545-561.
  4. 4.Wang H, Zhu Y, Wei H, et al. Ultrasound-guided local corticosteroid injection for carpal tunnel syndrome: a meta-analysis of randomized controlled trials. Clin Rehabil. 2021;35(11):1506-1517.
  5. 5.Yang FA, Shih YC, Hong JP, et al. Ultrasound-guided corticosteroid injection for patients with carpal tunnel syndrome: a systematic review and meta-analysis of randomized controlled trials. Sci Rep. 2021;11(1):10417.

Clinical Inquiries provides answers to questions submitted by practicing family physicians to the Family Physicians Inquiries Network (FPIN). Members of the network select questions based on their relevance to family medicine. Answers are drawn from an approved set of evidence-based resources and undergo peer review. The strength of recommendations and the level of evidence for individual studies are rated using criteria developed by the Evidence-Based Medicine Working Group (https://www.cebm.net).

The complete database of evidence-based questions and answers is copyrighted by FPIN. If interested in submitting questions or writing answers for this series, go to https://www.fpin.org or email questions@fpin.org.

Copyright © Family Physicians Inquiries Network. Used with permission.

This series is coordinated by John E. Delzell Jr., MD, MSPH, associate medical editor.

A collection of FPIN’s Clinical Inquiries published in AFP is available at https://www.aafp.org/afp/fpin.

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