Case Report: Acute Infectious Mononucleosis Mimicking Acute Acalculous Cholecystitis in an Adult

Ha Rio; Naomi Malam; Derek Nguyen

Reporting Number Needed to Treat Requires Standardization

Feb 2026

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Letters to the Editor

Case Report: Acute Infectious Mononucleosis Mimicking Acute Acalculous Cholecystitis in an Adult

American Family Physician. 2026;113(2):112-113.

Author disclosure: No relevant financial relationships.

Ha Rio, DO, MPH

Denver, Colorado

Naomi Malam, MD, MSPH

Denver, Colorado

naomi.malam@cuanschutz.edu

Derek Nguyen, MD

Denver, Colorado

Author disclosure: No relevant financial relationships.

1.Womack J, Jimenez M. Common questions about infectious mononucleosis. Am Fam Physician. 2015;91(6):372-376.
2.Rea TD, Russo JE, Katon W, et al. Prospective study of the natural history of infectious mononucleosis caused by Epstein-Barr virus. J Am Board Fam Pract. 2001;14(4):234-242.
3.Tsiakalos A, Schinas G, Karatzaferis A, et al. Acalculous cholecystitis as a complication of primary Epstein-Barr virus infection: a case-based scoping review of the literature. Viruses. 2024;16(3):463.

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