Articles
ADHD in Children: Common Questions and Answers
Attention-deficit/hyperactivity disorder (ADHD) is the most common neurodevelopmental condition in U.S. children and affects 8.4% of children between two and 17 years of age. Only 62% are treated with medication, less than one-half receive behavior treatment, and nearly one…
Nonalcoholic Fatty Liver Disease: Common Questions and Answers on Diagnosis and Management
Nonalcoholic fatty liver disease is the most common form of liver disease in the United States. Nonalcoholic fatty liver follows an indolent course. Nonalcoholic steatohepatitis is more likely to lead to cirrhosis and increases the risk of death from cardiovascular disease…
Oral Manifestations of Commonly Prescribed Drugs
Many adverse drug events present intra- or periorally in isolation or as a clinical symptom of a systemic effect. Clinical recognition and treatment of adverse drug events are important to increase patient compliance, to manage drug therapy, or to detect early signs of…
Editorials
Evidence to Avoid Overtesting and Overuse in Diabetes Mellitus and Other Diseases
Overuse is the use of medical interventions for which the potential harms exceed the potential benefits; this is in contrast to care that is truly necessary, supported by evidence, and likely to provide a net benefit to the patient.1 Various initiatives attempt to help…
AFP Clinical Answers
Augmentation Therapy, Menstrual Bleeding, VTE, Pancreatic Cancer, Acute Kidney Injury
What is the evidence for augmentation therapy in patients with treatment-resistant depression? | Are hormonal contraceptives effective in decreasing heavy menstrual bleeding? | What testing should be used to diagnose venous thromboembolism (VTE)? | Which patients should be…
Putting Prevention Into Practice
Behavioral Counseling Interventions to Prevent Sexually Transmitted Infections
A 24-year-old cisgender woman presents to your primary care clinic for a routine physical examination. Her only medication is an etonogestrel (Implanon) 68-mg implant for birth control. She reports occasional vaping of electronic cigarettes and states that she does not drink…
Photo Quiz
Recurrent Facial Rash
A healthy 34-year-old patient presented with a worsening facial rash that first appeared about two years earlier. The rash was initially painless but developed a moderately intense burning sensation with repeated flare-ups. There was no scarring or pruritus.
STEPS
Oral Semaglutide (Rybelsus) for the Treatment of Type 2 Diabetes Mellitus
Oral semaglutide (Rybelsus) is a glucagon-like peptide-1 (GLP-1) receptor agonist labeled as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. It reduces hyperglycemia by increasing insulin secretion and decreasing glucagon…
Practice Guidelines
Autism Spectrum Disorder: Updated Guidelines from the American Academy of Pediatrics
Key Points for Practice
POEMs
U.S. Preventive Services Task Force
Behavioral Counseling Interventions to Prevent Sexually Transmitted Infections: Recommendation Statement
The USPSTF recommends behavioral counseling for all sexually active adolescents and for adults who are at increased risk for sexually transmitted infections (STIs) (Table 1). B recommendation.
Information from Your Family Doctor
Nonalcoholic Fatty Liver Disease
Nonalcoholic fatty liver disease (or NAFLD for short) is a buildup of fat in the liver that is not caused by drinking alcohol. It is the most common liver disease in the United States.

