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STEPS
New Drug Reviews

Resmetirom (Rezdiffra) for the Treatment of Noncirrhotic Nonalcoholic Steatohepatitis With Moderate to Advanced Fibrosis

Smriti Ohri, MD
Maria Summa, PharmD, BCPS, BCACP

American Family Physician. 2024;110(3):313-314.

Author disclosure: No relevant financial relationships.

SMRITI OHRI, MD, Oregon Health & Science University, Portland, Oregon.

MARIA SUMMA, PharmD, BCPS, BCACP, UCONN Health, Farmington, Connecticut.

Author disclosure: No relevant financial relationships.

  1. 1.DailyMed. Drug label information. Rezdiffra—resmetirom tablet, coated. Accessed May 23, 2024. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e67ea09f-a840-439c-86c8-f98585f978b2
  2. 2.Rezdiffra (resmetirom) tablets, for oral use. Highlights of prescribing information. Revised March 2024. Accessed April 29, 2024. https://www.accessdata.fda.gov/drugsatfda_docs/label/2024/217785s000lbl.pdf
  3. 3.Harrison SA, Bedossa P, Guy CD, et al.; MAESTRO-NASH Investigators. A phase 3, randomized, controlled trial of resmetirom in NASH with liver fibrosis. N Engl J Med. 2024;390(6):497-509.

STEPS new drug reviews cover Safety, Tolerability, Effectiveness, Price, and Simplicity. Each independent review is provided by authors who have no financial association with the drug manufacturer.

This series is coordinated by Allen F. Shaughnessy, PharmD, assistant medical editor.

A collection of STEPS published in AFP is available at https://www.aafp.org/afp/steps.

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