Diagnosis of Acute Pancreatitis Using a Clinical Risk Score

Mark H. Ebell, MD, MS

American Family Physician. 2025;112(3):322-323.

Author disclosure: No relevant financial relationships.

This clinical content conforms to AAFP criteria for CME.

MARK H. EBELL MD, MS, Department of Family Medicine, Michigan State University, East Lansing

Address correspondence to Mark H. Ebell MD, MS, at ebell@msu.edu.

Author disclosure: No relevant financial relationships.

1.Walkowska J, Zielinska N, Tubbs RS, et al. Diagnosis and treatment of acute pancreatitis. Diagnostics (Basel). 2022;12(8):1974.
2.Kemppainen EA, Hedström JI, Puolakkainen PA, et al. Rapid measurement of urinary trypsinogen-2 as a screening test for acute pancreatitis. N Engl J Med. 1997;336(25):1788-1793.
3.Rompianesi G, Hann A, Komolafe O, et al. Serum amylase and lipase and urinary trypsinogen and amylase for diagnosis of acute pancreatitis. Cochrane Database Syst Rev. 2017(4):CD012010.
4.Jin DX, Lacson R, Eskian M, et al. Prospective validation of a prediction model for the diagnosis of acute pancreatitis. JAMA Netw Open. 2024;7(6):e2419014.
5.Jin DX, Lacson R, Cochon LR, et al. A clinical model for the early diagnosis of acute pancreatitis in the emergency department. Pancreas. 2018;47(7):871-879.
6.Banks PA, Bollen TL, Dervenis C, et al.; Acute Pancreatitis Classification Working Group. Classification of acute pancreatitis—2012: revision of the Atlanta classification and definitions by international consensus. Gut. 2013;62(1):102-111.

This guide is one in a series that offers evidence-based tools to assist family physicians in improving their decision-making at the point of care.

This series is coordinated by Mark H. Ebell, MD, MS, deputy editor for evidence-based medicine.

A collection of Point-of-Care Guides published in AFP is available at https://www.aafp.org/afp/poc.

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