Interventions for Smokeless Tobacco Cessation

Kento Sonoda, MD, AAHIVS, FAAFP, FASAM,

Galen Hoft, DO, MPH,

Saint Louis University, St. Louis, Missouri

American Family Physician. 2025;112(6):608-609.

Author disclosure: No relevant financial relationships.

This clinical content conforms to AAFP criteria for CME.

Author disclosure: No relevant financial relationships.

1.Livingstone-Banks J, Vidyasagaran AL, Croucher R, et al. Interventions for smokeless tobacco use cessation. Cochrane Database Syst Rev. 2025(4):CD015314.
2.Cornelius ME, Loretan CG, Jamal A, et al. Tobacco product use among adults–United States, 2021. MMWR Morb Mortal Wkly Rep. 2023;72(18):475-483.
3.Gil GF, Anderson JA, Aravkin A, et al. Health effects associated with chewing tobacco: a Burden of Proof study. Nat Commun. 2024;15(1):1082.
4.Theodoulou A, Chepkin SC, Ye W, et al. Different doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation. Cochrane Database Syst Rev. 2023(6):CD013308.
5.Hajizadeh A, Howes S, Theodoulou A, et al. Antidepressants for smoking cessation. Cochrane Database Syst Rev. 2023(5):CD000031.
6.WHO Clinical Treatment Guideline for Tobacco Cessation in Adults. World Health Organization; 2024.

These are summaries of reviews from the Cochrane Library.

This series is coordinated by Corey D. Fogleman, MD, assistant medical editor.

A collection of Cochrane for Clinicians published in AFP is available at https://www.aafp.org/afp/cochrane.

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