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Am Fam Physician. 2023;108(5):513-514

Author disclosure: No relevant financial relationships.

DrugDosageDose formCost*
BaricitinibInitial dosage: 2 mg once dailyTablets: 1 mg,$2,770 (1-mg and 2-mg tablets)
(Olumiant)If hair growth does not occur, increase to 4 mg once daily2 mg, 4 mg$5,530 (4-mg tablets)

Baricitinib (Olumiant) is labeled for the treatment of severe alopecia areata in adults.1 It is a Janus kinase inhibitor that interrupts cytokine signaling in the Janus kinase 1 and 2 pathways, leading to hair regrowth.2 Baricitinib is also labeled for the treatment of patients with certain types of rheumatoid arthritis and some patients hospitalized with COVID-19.1

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STEPS new drug reviews cover Safety, Tolerability, Effectiveness, Price, and Simplicity. Each independent review is provided by authors who have no financial association with the drug manufacturer.

This series is coordinated by Allen F. Shaughnessy, PharmD, assistant medical editor.

A collection of STEPS published in AFP is available at

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