Website maintenance is scheduled for Saturday, October 12, and Sunday, October 13. Short disruptions may occur during these days.

brand logo

Am Fam Physician. 2024;109(5):472-473

Author disclosure: No relevant financial relationships.

Fecal microbiota spores, live-brpk (Vowst) is a capsule of bacterial spore suspension taken orally. It is labeled for the prevention of Clostridioides difficile infection in adults who have recurrent C. difficile infection (i.e., three or more episodes within 12 months). Vowst is taken 2 to 4 days following antibiotic therapy for recurrent C. difficile infection. It is manufactured from human donor fecal matter that contains live, purified Firmicutes spores, which are thought to restore intestinal flora.1

DrugDosageDose formCost*
Fecal microbiota spores, live-brpk (Vowst)Four capsules taken orally once daily on an empty stomach for 3 consecutive daysCapsule (containing between 1 × 106 and 3 × 107 Firmicutes spore colony-forming units in 92% ± 4% glycerol in saline)$19,500
Already a member/subscriber?  Log In

Subscribe

From $165
  • Immediate, unlimited access to all AFP content
  • More than 130 CME credits/year
  • AAFP app access
  • Print delivery available
Subscribe

Issue Access

$59.95
  • Immediate, unlimited access to this issue's content
  • CME credits
  • AAFP app access
  • Print delivery available
Purchase Access:  Learn More

STEPS new drug reviews cover Safety, Tolerability, Effectiveness, Price, and Simplicity. Each independent review is provided by authors who have no financial association with the drug manufacturer.

This series is coordinated by Allen F. Shaughnessy, PharmD, assistant medical editor.

A collection of STEPS published in AFP is available at https://www.aafp.org/afp/steps.

Continue Reading

More in AFP

More in PubMed

Copyright © 2024 by the American Academy of Family Physicians.

This content is owned by the AAFP. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. This material may not otherwise be downloaded, copied, printed, stored, transmitted or reproduced in any medium, whether now known or later invented, except as authorized in writing by the AAFP.  See permissions for copyright questions and/or permission requests.