Articles
Atrial Fibrillation: Common Questions and Answers About Diagnosis and Treatment
Atrial fibrillation is the most common cardiac dysrhythmia in adults in the primary care setting. Diagnosis is based on history and physical examination findings and should be confirmed with 12-lead electrocardiography. Treatment includes rate and rhythm control; goals of…
Depression: Managing Resistance and Partial Response to Treatment
Treatment-resistant depression is absence of remission despite trials of two or more antidepressant medications; partial response to treatment is less than 50% reduction in depression-rating scores. Management includes adding psychotherapy, switching antidepressant medication…
Evaluation and Treatment of Nausea and Vomiting in Adults
In the absence of alarm symptoms, nausea and vomiting are typically treated symptomatically and without an extensive evaluation. Chronic symptoms require a careful history to narrow the differential diagnosis. When a specific etiology is not identified, a serotonin antagonist…
Substance Misuse in Adults: A Primary Care Approach
The medical approach to substance use has significantly changed over the past decade. New tools for prevention, screening, assessment, and treatment have been adopted, and family physicians are well positioned to provide prevention and management.
Acute Pericarditis: Rapid Evidence Review
This article reviews patient-oriented evidence to guide the diagnosis and management of acute pericarditis.
Falls in Older Adults: Approach and Prevention
Clinicians should screen older adults for fall risk, and if results are abnormal, multicomponent interventions are indicated. These include optimizing care of chronic medical conditions, evaluating home safety, and avoiding polypharmacy and drugs that increase fall risk.
Editorials
Diagnostic and Therapeutic Advances in Cystic Fibrosis: How Family Physicians Can Partner in Care
Patients with cystic fibrosis are living longer, healthier lives and are now facing many of the same ongoing health challenges as people without the condition.
Anxiety Screening Is Unlikely to Improve Mental Health Outcomes
Adding anxiety screening tests takes time away from critical health care tasks and is not likely to benefit patients compared with good standard care.
AFP Clinical Answers
Esophageal Cancer, Uterine Bleeding, HIV, Bariatric Surgery and Pregnancy, Venous Thromboembolism, Renal Colic
Key clinical questions and their evidence-based answers directly from the journal’s content, written by and for family physicians.
Medicine by the Numbers
Hyaluronic Acid Products for Chronic Wound Healing
Because of the significant risk of blinding bias and imprecision in the results as well as inadequate assessment of harms, a color recommendation of yellow (unclear benefits) is assigned for use of hyaluronic acid for chronic wounds.
Cochrane for Clinicians
Saw Palmetto for the Treatment of Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia
Saw palmetto, alone or in combination with other phytotherapeutic agents, does not improve urologic symptoms or quality of life in the short term (3 to 6 months) or long term (12 to 17 months). Also, it does not cause significant adverse events.
Antidepressants to Aid in Smoking Cessation
Bupropion facilitates tobacco cessation reported at 6 months of follow-up compared with placebo or no pharmacological treatment. More people discontinue using bupropion due to adverse effects than those using placebo or no pharmacological treatment.
U.S. Preventive Services Task Force
Screening for Anxiety Disorders in Adults
The USPSTF recommends screening for anxiety disorders in adults, including pregnant and postpartum persons. The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for anxiety disorders in older adults.
Putting Prevention Into Practice
Screening for Anxiety Disorders in Adults
This PPIP quiz is based on the recommendations of the USPSTF.
Implementing AHRQ Effective Health Care Reviews
Pharmacotherapy for Adults With Alcohol Use Disorder
Effects attributed to medications beyond nonpharmacologic interventions and placebo are reviewed.
FPIN's Clinical Inquiries
Baclofen for Alcohol Use Disorder
Baclofen with psychosocial therapy is modestly effective in helping patients with AUD achieve abstinence, increasing abstinent days by approximately 10%. A total of 40% to 50% of patients can achieve or maintain abstinence at 1 year after treatment initiation.
Photo Quiz
Persistent Pink Nodules and Hyperpigmented Plaques on Trunk and Extremities
A 68-year-old woman presented with persistent lesions on her trunk and extremities.
Red, Verrucous Plaque on the Forearm
A 63-year-old man presented with a nonpainful skin lesion on his left forearm.
Diagnostic Tests
Role of sFlt-1/PlGF Ratio in Diagnosing Preeclampsia
The sFlt-1/PlGF ratio cutoff must be standardized and further validated with additional clinical trials before implementation in the prediction and diagnosis of preeclampsia.
STEPS
Fecal Microbiota Spores, Live-Brpk (Vowst) to Prevent Clostridioides difficile Infection
Vowst is simple to administer, well tolerated, and relatively effective for patients with recurrent C. difficile infection. However, it is significantly expensive. It may be considered for patients who have had 3 or more episodes of C. difficile infection within 12 months.
Curbside Consultation
Firearm Injury Prevention: Practical Office Tips
Framework for how physicians can engage in patient-centered discussions that promote firearm injury prevention.
POEMs
Practice Guidelines
Evaluation of Mild Traumatic Brain Injury in Adults: Guidelines From the ACEP
The American College of Emergency Physicians (ACEP) has published new guidelines for evaluation of mild TBI.
Management of First-Episode Psychosis and Schizophrenia: Guidelines From the VA/DoD
The U.S. Department of Veterans Affairs and U.S. Department of Defense (VA/DoD) published new recommendations for diagnosing and managing schizophrenia and first-episode psychosis.
