Previous article
Methotrexate for Juvenile Idiopathic Arthritis
May 2025
Next article
Transcutaneous Electrical Nerve Stimulation for Pain Control in Women With Primary Dysmenorrhea
Cochrane for Clinicians

Sodium-Glucose Cotransporter-2 Inhibitors for People With Chronic Kidney Disease and Diabetes

Tracy Johns, PharmD, MSMS, BCACP,
USF College of Medicine, Tampa, Florida

American Family Physician. 2025;111(5):404-405.

Author disclosure: No relevant financial relationships.

This clinical content conforms to AAFP criteria for CME.

Author disclosure: No relevant financial relationships.

  1. 1.Natale P, Tunnicliffe DJ, Toyama T, et al. Sodium-glucose co-transporter protein 2 (SGLT2) inhibitors for people with chronic kidney disease and diabetes. Cochrane Database Syst Rev. 2024(5):CD015588.
  2. 2.Centers for Disease Control and Prevention. National diabetes statistics report. Accessed November 25, 2024. https://www.cdc.gov/diabetes/php/data-research
  3. 3.American Diabetes Association Professional Practice Committee. 10. Cardiovascular disease and risk management: Standards of Care in Diabetes–2024. Diabetes Care. 2024;47(suppl 1):S179-S218.
  4. 4.National Institute for Health and Care Excellence. Dapagliflozin for treating chronic kidney disease. Technology appraisal guidance [TA775]. Published March 9, 2022. Accessed November 25, 2024. www.nice.org.uk/guidance/ta775
  5. 5.Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2024 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int. 2024;105(4S):S117-S314.

These are summaries of reviews from the Cochrane Library.

This series is coordinated by Corey D. Fogleman, MD, assistant medical editor.

A collection of Cochrane for Clinicians published in AFP is available at https://www.aafp.org/afp/cochrane.

Previous article
Methotrexate for Juvenile Idiopathic Arthritis
May 2025
Next article
Transcutaneous Electrical Nerve Stimulation for Pain Control in Women With Primary Dysmenorrhea

Current issue

May 2026

May 2026

Copyright © 2026 by the American Academy of Family Physicians.

This content is owned by the AAFP. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. This material may not otherwise be downloaded, copied, printed, stored, transmitted or reproduced in any medium, whether now known or later invented, except as authorized in writing by the AAFP. See permissions for copyright questions and/or permission requests.