Previous article
Calcium Supplementation for Improving Pregnancy and Infant Outcomes (Other Than for Preventing or Treating Hypertension)
Jan 2026
Next article
Swollen Forehead
Cochrane for Clinicians

Discontinuing Antihypertensive Drugs in Adults 50 Years and Older

Mei-Li Laracuente, MD, PhD,
Arindam Sarkar, MD, FAAFP,
Baylor College of Medicine, Houston, Texas

American Family Physician. 2026;113(1):20.

Author disclosure: No relevant financial relationships.

This clinical content conforms to AAFP criteria for CME.

Author disclosure: No relevant financial relationships.

  1. 1.Gnjidic D, Langford AV, Jordan V, et al. Withdrawal of antihypertensive drugs in older people. Cochrane Database Syst Rev. 2025(3):CD012572.
  2. 2.Jones DW, Ferdinand KC, Taler SJ, et al. 2025 AHA/ACC/AANP/AAPA/ABC/ACCP/AC PM/AGS/AMA/ASPC/NMA/PCNA/SGIM guideline for the prevention, detection, evaluation and management of high blood pressure in adults: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Hypertension. 2025;82(10):e212-e316.
  3. 3.Sheppard JP, Koshiaris C, Stevens R, et al. The association between antihypertensive treatment and serious adverse events by age and frailty: a cohort study. PLoS Med. 2023;20(4):e1004223.
  4. 4.By the 2023 American Geriatrics Society Beers Criteria® Update Expert Panel. American Geriatrics Society 2023 updated AGS Beers Criteria® for potentially inappropriate medication use in older adults. J Am Geriatr Soc. 2023;71(7):2052-2081.
  5. 5.O'Mahony D, Cherubini A, Guiteras AR, et al. STOPP/START criteria for potentially inappropriate prescribing in older people: version 3. Eur Geriatr Med. 2023;14(4):625-632.

These are summaries of reviews from the Cochrane Library.

This series is coordinated by Corey D. Fogleman, MD, assistant medical editor.

A collection of Cochrane for Clinicians published in AFP is available at https://www.aafp.org/afp/cochrane.

Previous article
Calcium Supplementation for Improving Pregnancy and Infant Outcomes (Other Than for Preventing or Treating Hypertension)
Jan 2026
Next article
Swollen Forehead

Current issue

May 2026

May 2026

Copyright © 2026 by the American Academy of Family Physicians.

This content is owned by the AAFP. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. This material may not otherwise be downloaded, copied, printed, stored, transmitted or reproduced in any medium, whether now known or later invented, except as authorized in writing by the AAFP. See permissions for copyright questions and/or permission requests.