January 2026

To assess the complex health needs of older adults, family physicians should use the Age-Friendly Health Systems model, which is based on the 4Ms framework: What Matters, Medication, Mentation, and Mobility.

Neonatal respiratory distress requires prompt diagnosis and management to prevent severe outcomes. Assessment within the first minute is essential. Initial management involves warming, drying, stimulation, airway positioning, and clearing secretions. Supportive respiratory care…

Diagnosis of resistant hypertension requires evaluation for comorbid conditions and exclusion of medication nonadherence and white coat hypertension. Before making the diagnosis, other possible causes of inadequate blood pressure control should be excluded, including suboptimal…

Vertebral compression fractures should first be treated conservatively with pharmacotherapy for pain relief and physical rehabilitation to maintain function. If pain control is inadequate, surgical intervention can be considered.

Recurrent ischemic stroke is a significant health concern, with 12% of patients experiencing recurrence within 5 years of the initial stroke. Effective prevention strategies focus on identifying stroke subtypes, controlling cardiovascular risk factors, and tailoring treatment…

Antiretroviral therapy has transformed HIV into a chronic condition; however, HIV-associated complications remain common, driven by persistent immune activation, inflammation, sedentary lifestyle, and poor diet. Primary care clinicians play a critical role through routine…

A recent Supreme Court ruling may bring significant changes to the USPSTF under the current administration, creating a real possibility that this valuable source of evidence-based preventive care recommendations will be transformed into a partisan tool.

Continuous, whole person primary care improves health, prevents disease, and keeps costs down.

A color of yellow has been assigned for gonadotropins vs continued clomiphene for ovulation induction with polycystic ovary syndrome because of low-certainty evidence for several outcomes.

Calcium supplementation may slightly reduce preterm birth rates between 34 and 37 weeks’ gestation, but it likely has little to no effect on preterm birth rates less than 34 weeks’ gestation or on the risk of low birth weight (less than 2,500 g).

Discontinuing antihypertensive drugs in adults 50 years or older may lead to a modest increase in blood pressure but does not significantly increase the risk of all-cause mortality, stroke, myocardial infarction, or hospitalizations.

A 6-year-old boy presented after waking up with swelling of his forehead and bilateral eyelids. He had not experienced recent falls, trauma, or travel. The patient had not been outdoors in the previous 24 hours, but it was unclear whether he had any insect bites. He had a…

A 66-year-old woman presented 2 months after implantation of a biventricular permanent pacemaker. She had no immediate complications after the procedure. Four weeks after the procedure, she noted new varicose veins in the upper portion of her left arm and pectoral area…

What is the optimal dose of sublingual buprenorphine for maintenance treatment of opioid use disorder (OUD)?

Is abdominal massage an effective treatment for functional constipation in adults?

Vonoprazan is superior to placebo for treatment of nonerosive gastroesophageal reflux disease, but currently there is a lack of head-to-head evidence to recommend it over other first-line therapies.

Prescribing GLP-1 receptor agonists for adolescents with obesity requires a thorough shared decision-making process. The conversation must transparently address not only the potential benefits and adverse effects but also the significant caveats.

POEMs

POEMs

POEMs

POEMs

Although the American Academy of Family Physicians (AAFP) has usually endorsed the immunization schedule published by the Centers for Disease Control and Prevention (CDC), which is typically based on the recommendation of the Advisory Committee of Immunization Practices (ACIP…

Elevated blood pressure (BP) is often seen in clinical settings, especially in acute care where the clinical significance can be difficult to determine. Although hypertensive emergencies occur in 0.2% of adult emergency department visits, mortality rates have decreased over the…

Reply: Jeffrey D. Tiemstra

Incorrect testing information. “Acute Monoarthritis: Diagnosis in Adults” (June 2025, p. 497) incorrectly stated in Table 1 that certain diagnostic tests can rule out causes of psoriatic arthritis. The online version of the article has been corrected to include the diagnostic…