Substance use disorders: Clinical guidance and practice resources

A concerned doctor consults a downcast patient in an office setting.

Comprehensive resources for family physicians to identify and manage substance use disorders.

Substance use is widespread in the United States. In 2023, more than 134 million Americans age 12 and older reported consuming alcohol in the past month, and more than 20% of them had an alcohol use disorder. More than 64 million people reported using a tobacco or nicotine vaping product in the past month, and some 47 million said they'd used illicit drugs, according to the National Center for Drug Abuse Statistics.

Patients struggling with opioid and other substance use disorders often rely on their family physicians to offer support and help them find the resources they need. This page features evidence-based strategies to promote behavior change and lead to positive patient outcomes as you provide office-based prevention, diagnosis and treatment.


Guidelines and recommendations

The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of primary care–based behavioral counseling interventions to prevent illicit drug use, including nonmedical use of prescription drugs, in children, adolescents and young adults.

See the full recommendation for more information.

The USPSTF recommends screening for unhealthy alcohol use in primary care settings in adults 18 or older, including pregnant women, and providing persons engaged in risky or hazardous drinking with brief behavioral counseling interventions to reduce unhealthy alcohol use.

See the full recommendation for more information.

The USPSTF recommends screening adults 18 and older for unhealthy drug use when services for diagnosis, treatment, and follow-up are available. The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for unhealthy drug use in adolescents.

See the full recommendation for more information.

24.9%

Americans age 12 and older who have used illegal drugs or misused prescription drugs within the last year (70.5 million people).

National Center for Drug Abuse Statistics

Tobacco use—including e-cigarettes—remains the leading preventable cause of disease, disability and death in the United States. Vaping, particularly among youth and adolescents, has added a new, urgent challenge for primary care providers.

Help your patients stop smoking, or prevent them from starting, with this comprehensive toolkit.

Tobacco and nicotine use: clinical guidance and practice resources

Screening for alcohol use can be complicated by the co-use of other substances, like tobacco and illicit drugs. Learn more about how to identify and manage alcohol use disorders in your patients.

Treating excessive alcohol use

Logo for the Opioid Response Network.

Opioid Response Network

Throughout the U.S., states, local communities, and neighborhoods, are experiencing an unprecedented increase in the number of opioid-related deaths. In response to this healthcare crisis, the American Academy of Addiction Psychiatry (AAAP) and its coalition of 27 national healthcare partner organizations, including the AAFP, formed the Opioid Response Network, formerly known as the STR-TA consortium, to provide training and technical assistance across the country focusing on the local level needs.

This initiative, funded by the Substance Abuse and Mental Health Services Administration, utilizes experienced prescribers and clinicians, including family physicians, in prevention, treatment, and recovery who are collaborating to facilitate access to evidence-based resources.

All 50 states and 7 territories have a designated Opioid Response (STR-TA) team, led by a Regional Technology Transfer Specialist (TTS), who coordinates the implementation of evidence-based practices. Family physicians and other additional consultants are also available to meet the requester's specific needs. Anyone can request technical assistance.

Submit a technical assistance request.

How to use the Opioid Response Network

  • 1. Identify a need

    Any type of project, topic or issue along the continuum of care (prevention, treatment, recovery) for the opioid epidemic can be requested and evaluated.

  • 2. Make a request

    Contact the Opioid Response Network and a Technical Transfer Specialist will contact you within 24 hours and begin working to address your needs.

  • 3. Get help

    Some of the things we can we can help you do:

    • Build a coalition
    • Provide training
    • Provide mentoring
    • Conduct educational meetings
    • Identify local resources
    • Create clinical teams

Encourage your chapter to host a substance use disorders (SUD) training using the substance use disorder kit.

Download the toolkit


Prevention is a critical part of addressing the opioid misuse in this country. The Opioid Response Network will work with your community to develop a program that works for you, such as:

  • Prevention programs

  • Safe opioid prescribing

  • Public awareness campaigns

  • Naloxone training

  • School programs

  • Coalition building

Evidence-based treatment of opioid use disorder, with medications and counseling, has proven to be effective. These can include:

  • Psychosocial interventions

  • Pharmacotherapy (i.e., buprenorphine, naltrexone, methadone)

  • Telepsychiatry

  • Pain management

  • Buprenorphine induction in ER

For long-term recovery to be successful, patients need a program that includes both counseling and medication. It’s a team effort between patients and their providers. Approaches include:


  • Medication-assisted recovery

  • Peer support/recovery coach

  • Recovery housing

  • Clinician/public health advocacy

  • Recovery coalition/community building

  • Integration of peers/peer supervision

Questions? Contact the Project Team.

Technical Assistance

If you need technical assistance to support evidence-based practices in the prevention, treatment and recovery of opioid use disorders in your community, submit a request.

Funding for this initiative was made possible (in part) by grant no. 1H79TI088037 from SAMHSA. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

Addiction Treatment and Care CME for Family Physicians

Free 3.75 CME course with excellent primer sessions for treating patients with SUD. Beneficial as a standalone or great to brush up on basics. Community discussion boards also available to discuss implementation in your practice.
Free CME

Related resources

Use Neighborhood Navigator to find nearby resources

This interactive tool can be used at the point-of-care to connect patients with support from local organizations.
Find Support

Inside Family Medicine podcast

In this episode of Inside Family Medicine, Jeffrey Quinlan, MD, FAAFP, a family physician and academic leader discusses his work with AAFP on FASD and delves into the rising concerns about cannabis use during pregnancy. He highlights the impact of alcohol and cannabis on maternal and child health, the importance of preconception counseling and effective strategies for family physicians to screen and counsel patients about substance use during pregnancy.


Patient education on FamilyDoctor.org

Information on how to recognize the signs and seek the right treatment.

Substance use disorder

Learn the differences among tolerance, dependence and addiction, how to spot the signs and get help.

Opioid addiction

Latest news