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Am Fam Physician. 2025;112(1):22-23

Author disclosure: No relevant financial relationships.

DrugDosageDose formCost of full course*
Benzgalantamine (Zunveyl)5 mg twice daily; increase as needed to 10 mg twice daily after 4 weeks, to a maximum dosage of 15 mg twice daily5-mg, 10-mg, and 15-mg delayed-release tabletsApproximately $800

Benzgalantamine (Zunveyl) is labeled for the treatment of mild to moderate Alzheimer disease in adults. It is metabolized to galantamine, which is a competitive and reversible cholinesterase inhibitor. Benzgalantamine is thought to prevent degradation of acetylcholine and enhance cholinergic function.1 There are no published clinical trials of benzgalantamine. It was approved for marketing based on evidence from bioavailability studies comparing it with galantamine immediate-release tablets and extended-release capsules.

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STEPS new drug reviews cover Safety, Tolerability, Effectiveness, Price, and Simplicity. Each independent review is provided by authors who have no financial association with the drug manufacturer.

This series is coordinated by Allen F. Shaughnessy, PharmD, assistant medical editor.

A collection of STEPS published in AFP is available at https://www.aafp.org/afp/steps.

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