• Articles

    Common Foot Fractures

    Sabrina Silver, Elizabeth Williams, Meghan L. Plunkett

    This article discusses types of foot fractures, common mechanisms of injury, nonsurgical management, and indications for orthopedic referral.

    Managing Selected Chronic Conditions in Hospitalized Patients

    Robert L. Gauer, Alain Abellada, Matthew Stewart, Ryan Kozloski

    This article reviews current evidence and recommendations to manage hypertension, diabetes mellitus, alcohol withdrawal syndrome, and venous thromboembolism risk in hospitalized patients.

    Acute Medication Poisoning

    Irbert L. Vega, Matthew K. Griswold, Dayne Laskey

    The number of deaths from poisonings increased 36% between 2019 and 2021, likely because of the public health crises of the opioid epidemic and the worsening of mental health associated with the COVID-19 pandemic. Family physicians may be involved in the triage, stabilization...

    Treatment of Chronic Insomnia in Adults

    Eric M. Matheson, Brandon David Brown, Alexei O. DeCastro

    Cognitive behavior therapy is the first-line treatment for chronic insomnia; if it is not available or effective, short-term pharmacologic treatment may be considered. Physicians must also treat any underlying conditions that may be contributing.

    Abnormal Uterine Bleeding Associated With Hormonal Contraception

    Sarina Schrager, Kelita Fox, Rachel Lee

    Treatment of abnormal uterine bleeding in those using hormonal contraception can include adjustment of drug dosage and formulation, adding nonsteroidal anti-inflammatory drugs, and changing contraceptive methods.

    Acute Uncomplicated UTIs in Adults: Rapid Evidence Review

    Peter K. Kurotschka, Ildikó Gágyor, Mark H. Ebell

    The typical presentation of a urinary tract infection (UTI) includes frequency, urgency, dysuria/burning sensation, nocturia, and suprapubic pain or tenderness. More than 80% of UTIs occur in women. Clinical decision aids that integrate clinical findings with urine findings...


    Insomnia: Advancements and Limitations of Current Management Strategies

    William J. Healy, Rami N. Khayat, Younghoon Kwon

    There is much hope for patients with chronic insomnia given the expanding pipeline of medications and access to cognitive behavior therapy for insomnia.

    Primary Care's Role in Eliminating Inequities in Kidney Transplant

    Brittany N. Watson

    Black patients with chronic kidney disease (CKD) are almost four times more likely to progress to end-stage renal disease (ESRD) than their White counterparts. The inequity in access to quality CKD and ESRD management and kidney transplants is multifactorial.

    AFP Clinical Answers

    Concussion in Children, Ill Returning Traveler, RSV Vaccination, Hypertension in Pregnancy, More

    Key clinical questions and their evidence-based answers directly from the journal’s content, written by and for family physicians.

    Graham Center Policy One-Pager

    Osteopathic Medical Schools Produce an Increasing Proportion of Family Medicine Residents

    Chrystal Pristell, Hoon Byun, Alison Huffstetler

    The Association of American Medical Colleges reported a shortage of 45,000 primary care phy-sicians in 2020 and projects shortages of 65,000 by 2025 and 104,900 by 2030. The shortage has been exacerbated by physician retirement due to the COVID-19 pandemic.

    Medicine by the Numbers

    Brexpiprazole as Adjunctive Therapy for Acute Treatment-Resistant Depression

    Hemali Shah, Eric Matheson

    The review presents moderate- to high-certainty data that brexpiprazole is effective as an adjunct for treatment-resistant depression in adults 18 to 65 years of age. Based on these results and limitations, we have assigned a color recommendation of yellow (uncertain benefits).

    Cochrane for Clinicians

    Systemic Pharmacologic Treatments for Plaque Psoriasis

    Karl T. Clebak, Michael T. Partin

    Infliximab, bimekizumab (Bimzelx), ixekizumab (Taltz), and risankizumab (Skyrizi) are the most effective medications for achieving a 90% reduction in symptoms among patients with moderate to severe plaque psoriasis.

    Cannabis Use for Cancer-Related Pain

    Kento Sonoda

    Does cannabis improve cancer-related pain control in adults compared with placebo or other standard analgesics?

    U.S. Preventive Services Task Force

    Screening and Preventive Interventions for Oral Health in Children and Adolescents Aged 5 to 17 Years

    The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of routine screening performed by primary care clinicians for oral health conditions, including dental caries, in children and adolescents aged 5 to 17 years. The USPSTF...

    Diagnostic Tests

    Lipoprotein(a) Testing for Atherosclerotic Cardiovascular Disease

    Steven Embry, Jordan Rennicke

    Lp(a) measurement can characterize a patient’s risk of ASCVD beyond conventional risk calcu-lators, but there are no data from randomized tri¬als showing that direct Lp(a) reduction decreases ASCVD events.

    Implementing AHRQ Effective Health Care Reviews

    Management of Postpartum Hypertensive Disorders of Pregnancy

    Tyler W. Barreto

    What are the effectiveness, benefits, and harms of management strategies for hypertensive disorders of pregnancy during the postpartum period?

    FPIN's Clinical Inquiries

    Exercise for Depression in Older Adults

    Sarah Hourston, Brian Bertsche, Brian Vukelic, Dominik Ose, Eliza Taylor, Kirsten Stoesser

    Exercise is beneficial for treating depression in adults older than 60 years. Exercise training is recommended for healthy older adults because it significantly decreases depressive symptoms.

    Photo Quiz

    A Pain in the Eye

    Kaitlin O'Malley, Stephen Jumper

    A 35-year-old man presented with discomfort in his left eye.

    Young Man With Shortness of Breath

    John Watkins, Oren Vromen, Tsvi Sirotkin, Ronit Elad

    A man presented with intermittent shortness of breath and paroxysmal cough.

    Diary of a Family Physician

    Diary of a Family Physician

    Christina Metzler Miller, Peter Lueninghoener

    First-person accounts from the front lines of family medicine.


    The Risk of Breast Cancer Overdiagnosis Is High in Older Women

    Allen F. Shaughnessy

    Normal Defecation Patterns in Healthy Young Children Vary by Age, Diet, and Place of Residence

    Henry C. Barry

    Acetaminophen and Ketorolac Are More Effective Than Morphine in Alleviating Pain in Adults With Renal Colic

    Henry C. Barry

    Esketamine Is Superior to Quetiapine for Remission of Treatment-Resistant Depression

    Mark H. Ebell

    Practice Guidelines

    Treating Patients With Eating Disorders: Guidelines From the American Psychiatric Association

    Michael J. Arnold

    These disorders can be difficult to recognize, and the American Psychiatric Association (APA) has released guidelines aimed to reduce the harm from eating disorders.

    Management of Anal Fissures: Guidelines From the American Society of Colon and Rectal Surgeons

    Michael J. Arnold

    The American Society of Colon and Rectal Surgeons has released guidelines for the treatment of anal fissures.

    Letters to the Editor

    Further Discussion Regarding Multicancer Early Detection Tests

    Sana Raoof, Eric A. Klein

    Reply: Chyke A. Doubeni, Philip E. Castle

    Low-Dose Naltrexone: A Possible Option for Fibromyalgia

    Manasa Irwin, Sarah Winter

    Information from Your Family Doctor

    Urinary Tract Infection (UTI)

    A urinary tract infection (UTI for short) is an infection in your bladder. It is also called cystitis (sis-TIE-tis). If you have a bladder infection, you may feel pain or burning when urinating or have an unusually strong urge to urinate. You may also urinate more often, see...



    Incorrect Grading Scale. In the article “Bell Palsy: Rapid Evidence Review” (April 2023, p. 415), one of the grades in the House-Brackman scale for classifying symptom severity of Bell palsy was inadvertently omitted in the right column of page 416. The last two grades should...


    Table Columns Switched. In the article “Growth Faltering and Failure to Thrive in Children” (June 2023, p. 597), the information in the “Water (oz)” and “Formula” columns was inadvertently switched in the “Liquid Formula” section of Table 4 (p. 601). Also, in the last...


    Incorrect Statistic. In the article “Preventing CVD in Women: Common Questions and Answers” (December 2023, p. 595), the numbers of cardiovascular events occurring in relation to age at onset of menopause were inadvertently listed in the wrong order in the first paragraph of...


    Misplaced Figures. In the article “Nontraumatic Subarachnoid Hemorrhage and Ruptured Intracranial Aneurysm: Recognition and Evaluation” (October 2023, p. 386), the images in the left column of Figure 2 (p. 389) were placed incorrectly, resulting in the accompanying figure...


    All editors in a position to control content for this activity, AFP journal, are required to disclose any relevant financial relationships. View disclosures.

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