March 2025

Articles

Acute Bronchitis: Rapid Evidence Review

Elie Mulhem, Erwin Patalinghug, Hany Eraqi

Acute bronchitis is defined as acute cough with symptoms of lower respiratory tract infection. This article provides a summary of the best available patient-oriented evidence for the diagnosis and management of acute bronchitis in the primary care setting.

Chronic Pelvic Pain in Women: Evaluation and Treatment

Erica S. Meisenheimer, Ann M. Carnevale

Chronic pelvic pain in women is most often the result of multiple coexisting pain conditions and central nervous system hypersensitivity, and management should follow an interdisciplinary approach to improve function and quality of life.

Pacifiers: Common Questions and Answers

David S. Garcia, Kara W. Garcia

Pacifier use reduces the risk of sudden infant death syndrome, primarily in the first 6 months of life, but it should not be introduced until breastfeeding has been well established.

Care of Infants and Children With Down Syndrome: Role of the Family Physician

Christopher W. Bunt, Stephanie K. Bunt

Down syndrome is the most commonly diagnosed chromosomal abnormality. Screening; immunizations; and health maintenance, emphasizing early intervention and comprehensive support services, vary based on age.

The Pretravel Consultation

Jedda Rupert, Timothy Groh, Rebecca Allen

Patients who will be traveling internationally should be advised to schedule dedicated pretravel assessments with their primary care physicians to identify hazards and guide risk-mitigation strategies. Travel safety measures should be itinerary specific and include infectious…

Editorials

The Empowerment of Consumers for Health: AI Accelerates a Long-Standing Trend

Joel Selanikio

The rise of AI represents another step toward empowering consumers to take control of their health decisions. This might mean the decline in low-acuity visits to physicians. Health care will need to refocus on higher acuity, less easily automated activities.

Updates to Management of Adults With Chronic Kidney Disease

Stephanie Toth-Manikowski, Howard Shaps, John Danziger

Kidney Disease: Improving Global Outcomes (KDIGO) updates related to new medications that can delay chronic kidney disease progression and recommendations for atherosclerotic cardiovascular disease risk assessment in patients with chronic kidney disease.

Inside AFP

The Evolution of Evidence-Based Medicine in American Family Physician

Jay Siwek, Mark H. Ebell, Allen F. Shaughnessy

By updating our content with the best evidence, AFP continues to innovate and be a leader in helping our readers provide high-quality care for patients.

Medicine by the Numbers

Nicotine Electronic Cigarettes for Smoking Cessation

Isobel Hunter, D. Jason Frasca

We have assigned a color recommendation of yellow (unclear benefits) for the use of e-cigarettes for smoking cessation on the basis of some promising results compared with current cessation treatments but insufficient long-term evidence and a high risk of bias within considered…

Cochrane for Clinicians

Exercise-Based Cardiac Rehabilitation for Adults With Heart Failure

JEFFREY BEVAN, TIMOTHY K. LYNCH, JEANMARIE B. REY

Exercise-based cardiac rehabilitation likely reduces the risk of all-cause hospital admission in adults who have heart failure with reduced or preserved ejection fraction. Exercise-based cardiac rehabilitation likely improves short-term health-related quality of life in adults…

High-Flow Nasal Cannula Therapy for Infants With Bronchiolitis

RYAN PAULUS, ANNE MOUNSEY, WESLEY ROTEN

High-flow nasal cannula (HFNC) treatment is appropriate for infants younger than 24 months with bronchiolitis. Compared with low-flow oxygen, use of HFNC treatment results in a modest reduction in length of hospital stay (ie, by 0.65 days) and need for treatment escalation with…

Diagnostic Tests

Temporal Artery Ultrasonography for the Diagnosis of Giant Cell Arteritis

Karissa Allan Thal, Amaal Starling, Fred Cohen

Temporal artery ultrasonography offers a noninvasive, lower-cost option for the diagnosis of GCA compared with biopsy. However, there is limited data to support replacing biopsy with ultrasonography. The American College of Rheumatology continues to recommend biopsy as the…

STEPS

Berdazimer (Zelsuvmi) for the Treatment of Molluscum Contagiosum

William Dabbs, Shauntá Chamberlin

Berdazimer is a complicated, long-term treatment for molluscum contagiosum. Its cost and inconvenience in preparation should be considered against the time-limited nature of molluscum contagiosum, with spontaneous clearing in 20% of patients at 3 months.

FPIN's Clinical Inquiries

Zuranolone (Zurzuvae) for Treatment of Severe Postpartum Depression in Adults

Serena Fang, Roya Sharifian, Vivian Cheng, Jon O. Neher

Zuranolone is an effective treatment for adults with severe postpartum depression.

Curbside Consultation

Caring for Adults With Intellectual Disabilities in the Community

Emily Johnson, Clarissa C. Kripke

When caring for a person with intellectual and developmental disabilities, clinicians should provide patients with options for community living, services, and supports, allowing them the opportunity to make their will and preferences known. With any major life change, a person…

Lown Right Care

Potential Downstream Harms of Routine Temperature Measurements in Well-Appearing Infants

Meredith Mitchell, Matthew Schefft, Elizabeth Wolf, Helen Haskell, John James

A collaboration between AFP and the Lown Institute promotes a vision of delivering health care that is based on the evidence, balanced in its approach, and focused on the patient.

Photo Quiz

Acute Left Shoulder Pain After a Weight Lifting Injury

Michael R. McNeely, Andrew P. Statkevich

A 30-year-old man presented with a left shoulder injury.

Pigmented Lesion on the Hard Palate

Keshavamurthy Vinay, Apoorva Sharma, Manavi Gupta

A 59-year-old man presented with a bluish-black lesion on the hard palate.

Point-of-Care Guides

Predicting the Risk of Esophageal Adenocarcinoma in People With Barrett Esophagus

Mark H. Ebell

In patients with Barrett esophagus, what is the annual risk of developing invasive esophageal adenocarcinoma?

POEMs

Practice Guidelines

Alcohol-Associated Liver Disease: Guidelines From the American College of Gastroenterology

Michael J. Arnold

The American College of Gastroenterology has released guidelines for management of alcohol-associated liver disease.

Letters to the Editor

FREE

Exercise Therapy for Chronic Low Back Pain

Robert Skully

Reply: Donald Clinton Maharty, Shaun Hines, Regina Bray-Brown

FREE

Prostate-Specific Antigen Testing in the Evaluation of Chronic Low Back Pain

Daniel Rosenberg

Reply: Donald Clinton Maharty, Shaun Hines, Regina Bray-Brown

CME Course Information

Evidence-based Medicine Toolkit

Strength of Recommendation Taxonomy

Advertising: Career Opportunities (PDF download)

Disclosures

All editors in a position to control content for this activity, AFP journal, are required to disclose any relevant financial relationships. View disclosures.

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