Afi M. Semenya, Stefan Pienkowski, Prakhya Bhatnagar
Diagnosis of acute or chronic urticaria is usually based on history and physical examination findings. Preferred acute urticaria treatment includes second-generation H1 antihistamines; first-line treatment of chronic urticaria follows a stepped plan that includes second...
Richard Moore, II, Claire L. Porter, Jama M. Darling
All adults should be screened at least once for hepatitis B using triple panel testing, and vaccination should be offered to all adults 19 to 59 years of age regardless of risk.
Richard Moore, II, Claire L. Porter, Jama M. Darling
Chronic hepatitis B infection is diagnosed when hepatitis B surface antigen is present for at least 6 months. Therapy with oral nucleoside/nucleotide analogues can reduce the risk of cirrhosis, hepatocellular carcinoma, and liver-related mortality.
Pamela R. Hughes, Nelson E. Shreve, Patrick A. Bloecher
Multiple myeloma is a hematologic malignancy of plasma cells that affects approximately 36,000 people annually in the United States, with a median age at diagnosis of 69 years. Diagnosis involves laboratory tests, imaging, and bone marrow analysis. Treatment is determined by...
Alexandria Cooke, Sara Conway, Leslie Griffin
Croup is a common childhood respiratory illness causing a characteristic barking cough, hoarseness, and inspiratory stridor. It is treated with corticosteroids and nebulized epinephrine. Recurrent croup should prompt evaluation for an underlying anatomic abnormality or...
Lindy Krebs, Barbara Durden, Aaron Saguil
Meningitis is the inflammation of the meninges from viral, bacterial, fungal, noninfectious, or unknown causes. Viral pathogens are responsible for up to 60% of cases. Meningitis may cause neck stiffness, fever, headache, and altered mentation.
Kathryn A. McKenna, Donna Cohen
Preconception, antepartum, and postpartum care for patients who are obese.
Judy Chertok, Navid Roder
Rapid changes in the drug supply, including additives and contaminants, can have profound clinical impacts. Since 2024, a new additive, medetomidine, has been implicated in overdose and complicated withdrawal in several major metropolitan areas.
Kelly Dougherty, Anuradha Jetty, Alison N. Huffstetler
Long-acting reversible contraceptives (LARCs), including intrauterine devices (IUDs) and etonogestrel single rod implants, are effective in preventing unintended pregnancy. In the post-Dobbs era, it is important for family physicians to expand access to LARCs because previous...
Ross Stanton, Joshua Lujan, Christina Valerio
A color recommendation of yellow (unclear benefits) is assigned for the use of sustained-release naltrexone for opioid dependence because of significant limitations of the findings.
Meera Sunder
Visual estimation of blood loss is not very sensitive (22%-48%) but is very specific (97%-99%) when used to diagnose postpartum hemorrhage in patients who deliver vaginally in a hospital setting. In contrast, using a calibrated drape plus observations (eg, heart rate, blood...
Alvin Soto-Soto, Alexis B. Reedy-Cooper
Children aged 1 to 2 years who begin using toothpaste with higher fluoride concentrations (1,000 ppm or more vs less than 1,000 ppm) are at increased risk of developing dental fluorosis (mottling or discoloration) in permanent teeth.
Jennifer Wolf, Jessica Fournier
Intranasal epinephrine is an alternative to current injectable forms of emergency epinephrine. It may be a functional tool for patients who are hesitant or resistant to using needles, but it is more expensive than current injectable options.
The USPSTF recommends screening for depression in the adult population, including pregnant and postpartum persons, as well as older adults. The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for suicide risk...
Iris R. Mabry-Hernandez, Susan J. Ching
This PPIP quiz is based on the recommendations of the USPSTF.
MaryAnn Dakkak, Dominique Sanchez, Helen Haskell, John James
A collaboration between AFP and the Lown Institute promotes a vision of delivering health care that is based on the evidence, balanced in its approach, and focused on the patient.
Henry C. Barry
David Slawson
David Slawson
Allen F. Shaughnessy
John Sauret, Nicolas Ciminelli
A 62-year-old man presented with a slowly growing left abdominal mass.
Alison Small, Lauryn Orsillo
An 11-year-old boy presented with a rash on his back, abdomen, arms, and legs.
Julia Swanson, Kathleen Lucier, Maikha Jean-Baptiste, Jon O. Neher
Physicians should counsel adults treated with sodium-glucose cotransporter-2 inhibitors about an increased risk of genital infections.
Megan Mendez Miller, Sesilya Whaley
The Q-Pad Test represents a novel, at-home method for measuring A1C, using menstrual blood. Although multiple small observational studies have shown close agreement with venous A1C values, limitations such as potential selection and observer bias, lack of independent...
Mark Ebell
In people 80 years and older taking a direct oral anticoagulant, who is at increased risk for major hemorrhage?
Michelle Nelson
This guideline from the American Heart Association and American Red Cross provides guidance on administering first aid.
MaryAnn Dakkak, Amy He, Amy Min He
The Endocrine Society has updated its guidelines on the evidence for vitamin D supplementation and testing for disease prevention.
Louis A. Kazal, Jr
Reply: James J. Arnold, David Villaneuva, Melissa Jane Puntkatalee
Schawanya K. Rattanapitoon, Nathkapach K. Rattanapitoon
Benjamin Silverberg
Funded Content by Wiley: This grant-funded resource should not be considered an AAFP endorsement or recommendation of the grantor’s products, services, policies, or procedures. Journal editors were not involved in the development of this content.
Incorrect CME Quiz answer. In the “Answers to This Issue's CME Quiz” box (February 2026, p. 201), the answer listed for Q7 was incorrect. The correct answer should have been listed as “B.” The online CME quiz has been corrected.
Incorrect algorithm information. “Newborn Respiratory Distress: Evaluation and Management” (January 2026, p. 37) included extraneous information in the “Follow neonatal resuscitation algorithm” section of Figure 1. The online version of the article has been corrected.
All editors in a position to control content for this activity, AFP journal, are required to disclose any relevant financial relationships. View disclosures.
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