• Articles

    Wheezing in Children

    Stephen D. Cagle, Jr, Hannah Hornsby, Justin J. Chin

    Up to 50% of children experience recurrent episodes of wheezing by age 5 years. The differential diagnosis varies depending on age of onset. Chest radiography is the recommended initial imaging study for those who have recurrent episodes without a clear etiology.

    Cervical Cancer Screening

    Amy Wiser, Jeffrey D. Quinlan

    The American Cancer Society and US Preventive Services Task Force (USPSTF) endorse three strategies for cervical cancer screening: cytology alone, cotesting, and primary HPV screening; primary HPV screening is preferred in current guidelines and the USPSTF draft recommendation.

    Infective Endocarditis: Diagnosis and Treatment

    Raman Nohria, Andrew Romaine, Gabryel Garcia-Sampson

    Endocarditis should be considered in any patient with fever or sepsis of unknown origin. Empiric intravenous antimicrobial therapy, infectious source control, and expert consultation are mainstays of initial treatment.

    Evaluation of Neck Masses in Adults

    Jason Wilbur, Valery L. Tran, Marc F. Doobay

    Neck masses in adults are mostly benign, but malignancy must be considered. Accurate and timely diagnosis of malignant masses is based on acuity (ie, acute [eg, infection], subacute [eg, malignancy], and chronic [eg, congenital, thyroid]), history, physical examination, and...

    Cardiomyopathy: A Guide for Primary Care

    Joseph Coppiano, Mark Carrasco, Irfan Asif

    This review focuses on nonischemic cardiomyopathies, covering classification, evaluation, management strategies, and guideline updates. Key topics include hypertrophic, arrhythmogenic, dilated, restrictive, peripartum, and takotsubo cardiomyopathies, with recommendations for...

    Impetigo: Rapid Evidence Review

    Diana T. Trang, Emily C. Buck, Daniel T. Schoenherr

    The diagnosis of impetigo is based primarily on clinical examination and should be suspected in patients with erythematous papules that progress to ruptured vesicles or bullae over 4 to 6 days. Topical mupirocin 2% ointment is first-line treatment for mild, nonbullous and...

    Editorials

    Menopause Management: When Hormone Therapy Is Appropriate

    Maya Bass, Rebecca E. Kasper

    “Do the best you can until you know better.

    Long-Term Use of Obesity Management Medications: Challenges and Discontinuation Strategies

    Tamim Rajjo, Dima Bechenati, Diana B. Collantes Hoyos, Meera Shah

    Obesity remains a major challenge in primary care. By 2030, it is projected that nearly one-half of adults in the United States will have obesity (body mass index of at least 30 kg/m2), and one-fourth will have severe obesity (body mass index of at least 35 kg/m2).1 Weight...

    Medicine by the Numbers

    PPIs for Prevention of NSAID-Induced Gastric or Duodenal Ulcers and Dyspepsia

    Megan D. Rodgers, Michael D. North

    Study Population: 12 parallel randomized controlled trials with 8,760 adult outpatients taking nonsteroidal anti-inflammatory drugs (NSAIDs) for more than 4 weeks across multiple centers and nations; patients received proton pump inhibitors (PPIs) for prevention of NSAID...

    AFP Clinical Answers

    Alzheimer Disease, Polycystic Ovary Syndrome, Carpal Tunnel Syndrome, Pyogenic Granulomas, Depression in Heart Disease, Urinary Tract Infections

    Should brexpiprazole be used in the treatment of patients with behavioral disturbance in Alzheimer disease? | Can antimüllerian hormone be used to diagnose PCOS? | Is ultrasound guidance necessary for treatment of carpal tunnel syndrome with injected corticosteroids? | Can...

    Cochrane for Clinicians

    DASH Diet for the Primary and Secondary Prevention of Cardiovascular Diseases

    Karl T. Clebak, Makayla Lagerman, Zakary Newberry

    In adults, does adhering to the Dietary Approaches to Stop Hypertension (DASH) diet reduce rates of cardiovascular events (eg, myocardial infarction [MI], stroke) or all-cause mortality compared with usual diet or other dietary interventions?

    Nonpharmacologic and Nonsurgical Treatment of Low Back Pain in Adults

    Jeffrey Leggit, Brayson Pawelczyk

    Are nonpharmacologic and nonsurgical treatment options safe and effective for nonspecific acute or chronic low back pain?

    Diary of a Family Physician

    Diary of a Family Physician

    Annette Chavez

    A middle-aged woman presents after a hysterectomy that was complicated by a postoperative aortic thrombus. She tested positive for factor V Leiden sequence variation; she has a family history but tested negative 10 years ago. The hospitalist told her that the test is now more...

    FPIN's Clinical Inquiries

    Target LDL-C Level or Fixed-Dose Treatment for ASCVD

    Richard Guthmann, Adam Korte, Robert Martin

    In patients with established atherosclerotic cardiovascular disease (ASCVD), should oral cholesterol medications be dosed to achieve a specific low-density lipoprotein cholesterol (LDLC) level or given as a fixed dose according to the patient's risk profile?

    Photo Quiz

    Hand Injury in a Pickleball Player

    Michael L. Grover, Jyoti Gurung, Erwin A. Kruger

    An active 81-year-old woman was evaluated 3 days after injuring her right hand while playing pickleball. After hitting the ball with extra force, she had immediately felt pain over the dorsum of her right hand. She then noticed progressive swelling of the affected area over...

    Infant With an Asymmetrical Smile

    Tracy Williams, Taylor Russell, Kristina Chaffee Khant

    A 4-month-old female infant presented for a well-child visit. Her parents were concerned about the left side of her face. Since birth, she had an asymmetrical smile, and her left eye could not be closed and had excessive tear production. She was otherwise healthy and met all...

    POEMs

    Systematic Review Supports Colchicine for Secondary Prevention of Atherosclerotic Cardiovascular Disease

    David Slawson

    For Women With Dense Breasts, Supplemental Screening With Contrast-Enhanced Mammography Is Similar to MRI

    Mark H. Ebell

    Computed Tomography Scans Are Projected to Increase Lifetime Cancer Risk

    Allen F. Shaughnessy

    As-Needed Budesonide Plus Albuterol Is Superior to Albuterol Alone for Poorly Controlled Mild Asthma

    Mark H. Ebell

    Practice Guidelines

    Management of Tinnitus: Guidelines From the VA/DoD

    Michael J. Arnold

    Tinnitus, the perception of sound without an external source, can be constant or intermittent and is most often secondary to auditory system damage. Patients with tinnitus can describe ringing, buzzing, hissing, sizzling, roaring, chirping, or other sounds. One in five people...

    Acute Migraine Treatment: Guidelines From the International Headache Society

    Michael J. Arnold

    Migraine headaches are common throughout the world. The International Headache Society (IHS) published guidelines for acute migraine medical treatment.

    Letters to the Editor

    Surgery vs Corticosteroid Injections for Carpal Tunnel Syndrome

    Diana Ly-Liu, José-Luis Andréu, Domingo Ly-Pen

    Reporting Number Needed to Treat Requires Standardization

    Richard Temple

    Case Report: Acute Infectious Mononucleosis Mimicking Acute Acalculous Cholecystitis in an Adult

    Ha Rio, Naomi Malam, Derek Nguyen

    Information from Your Family Doctor

    Self-Collected Samples for Cervical Cancer Screening: What You Need to Know

    The cervix is the lowest part of your uterus or womb where it joins the vagina. It allows for bleeding during your period and opens to let the baby out during birth. It is pink and the size of a coin. Cancer can develop in the cervix.

    Corrections

    Correction

    Incorrect drug information. “Mastitis: Rapid Evidence Review” (August 2024, p. 174) incorrectly listed amoxicillin as a treatment for bacterial mastitis in Table 5. The online version of the article has been corrected.



    Disclosure

    All editors in a position to control content for this activity, AFP journal, are required to disclose any relevant financial relationships. View disclosures.


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